Histologic Diagnosis of Inflammatory Skin Diseases

Images

…0.5.13B: Ova of mites within a burrow in the cornified layer = Scabies The infiltrate consists of lymphocytes, plasma cells, and eosinophils, all of which are expected in a lesion of scabies. 10.5.14A: Perivascular and interstitial dermatitis +…

Differential Diagnosis in Dermatopathology

Discussions

…me lymphocytes is much more notable than it ever is in nodular scabies. Lymphocytes in lymphomatoid papulosis are larger and more pleomorphic than those in nodular scabies, have prominent nucleoli, often are multinucleate, and even may display aberra…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Nodular and Diffuse Dermatitis

…ytes, plasma cells, and eosinophils, as is the case in nodular scabies (Fig. 5.198). Not uncommonly in that particular manifestation of scabies in which no sign of the mite, her progeny, or her detritus is apparent in the stratum corneum, large lymph…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

In this section, algorithms used to reach specific diagnosis are predicated on “nonspecific” findings recognized best at higher magnification. Other changes requisite for specific diagnoses, i.e., denominators that are essential, then ar…

Histologic Diagnosis of Inflammatory Skin Diseases

Study By Disease

…is (Quiz #602) Sarcoidosis (Quiz #662) Sarcoidosis (Quiz #705) Scabies (Quiz #2) Scabies (Quiz #346) Scabies (Quiz #542) Scabies (Quiz #543) Schamberg’s disease (Quiz #44) Scleredema adultorum (Buschke) (Quiz #40) Sebaceous carcinomas in a pati…

Histologic Diagnosis of Inflammatory Skin Diseases

Parasitic infestations

…7. Falk ES, Eide TJ. Histologic and clinical findings in human scabies. Int J Dermatol 1981;20:600–05. Fernandez N, Torres A, Ackerman AB. Pathologic findings in human scabies. Arch Dermatol 1977;113:320–24. Guiral J, Rodrigo A, Tello E. Subcutaneous…

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

APOPTOSIS [Gk. apo- (away from) + ptosis (a falling)]: Reputed to be a specific type of cell death in which dead cells are said to undergo fragmentation by implosion with subsequent phagocytosis of nuclear debris (Fig. 3.40). The process is claimed…

Histologic Diagnosis of Inflammatory Skin Diseases

Selection of the Site

Because many inflammatory diseases of the skin, e.g., dermatitis herpetiformis, nummular dermatitis, scabies, Grover’s disease, and eosinophilic folliculitis, are exquisitely pruritic, scratching is an inevitable consequence, and signs of exco…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…nce of the “bite” of an insect; the female mite of scabies may induce nodules of lymphocytes and eosinophils (so-called nodular scabies) and the bite of a tick may bring into being a dense nodular mixed-cell infiltrate of lymphocytes, his…