Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

In this section, algorithms used to reach specific diagnosis are predicated on “nonspecific” findings recognized best at higher magnification. Other changes requisite for specific diagnoses, i.e., denominators that are essential, then ar…

Histologic Diagnosis of Inflammatory Skin Diseases

Study By Disease

…is (Quiz #602) Sarcoidosis (Quiz #662) Sarcoidosis (Quiz #705) Scabies (Quiz #2) Scabies (Quiz #346) Scabies (Quiz #542) Scabies (Quiz #543) Schamberg’s disease (Quiz #44) Scleredema adultorum (Buschke) (Quiz #40) Sebaceous carcinomas in a pati…

Histologic Diagnosis of Inflammatory Skin Diseases

Parasitic infestations

…7. Falk ES, Eide TJ. Histologic and clinical findings in human scabies. Int J Dermatol 1981;20:600–05. Fernandez N, Torres A, Ackerman AB. Pathologic findings in human scabies. Arch Dermatol 1977;113:320–24. Guiral J, Rodrigo A, Tello E. Subcutaneous…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…nce of the “bite” of an insect; the female mite of scabies may induce nodules of lymphocytes and eosinophils (so-called nodular scabies) and the bite of a tick may bring into being a dense nodular mixed-cell infiltrate of lymphocytes, his…

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

APOPTOSIS [Gk. apo- (away from) + ptosis (a falling)]: Reputed to be a specific type of cell death in which dead cells are said to undergo fragmentation by implosion with subsequent phagocytosis of nuclear debris (Fig. 3.40). The process is claimed…

Histologic Diagnosis of Inflammatory Skin Diseases

Selection of the Site

Because many inflammatory diseases of the skin, e.g., dermatitis herpetiformis, nummular dermatitis, scabies, Grover’s disease, and eosinophilic folliculitis, are exquisitely pruritic, scratching is an inevitable consequence, and signs of exco…

Differential Diagnosis in Dermatopathology

Discussions

…s reaction replete with lymphoid follicles. Nodular lesions of scabies have denser and deeper infiltrates than conventional papules of scabies in which mites and their products, such as fecal nuggets, are housed in burrows in the cornified layer. Oth…

Differential Diagnosis in Dermatopathology

Urticarial reaction to an arthropod assault vs. Urtica

Papules, nodules, vesicles, and sometimes bullae that develop in response to “bites” of arthropods, among the most common offenders being mosquitoes, bedbugs, and mites of scabies….