Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ts, such as by “bites” of insects and of mites of scabies, sometimes induce changes of small-vessel vasculitis as manifested by fibrin in the wall of venules, as shown here, thrombi in lumen of venules, or both of them together. 10….

Differential Diagnosis in Dermatopathology

Discussions

Nodular scabies and lymphomatoid papulosis have many attributes histopathologic in common. Both consist of infiltrates whose pattern is superficial and deep, perivascular, and interstitial, and whose population of cells may be mixed, i.e., small lym…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Nodular and Diffuse Dermatitis

…tes, plasma cells, and eosinophils, as is the case in nodular scabies (Fig. 5.198). Not uncommonly in that particular manifestation of scabies in which no sign of the mite, her progeny, or her detritus is apparent in the stratum corneum, large lympho…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…alone or in combination, in a tunnel in the stratum corneum = Scabies + Intracytoplasmic amphophilic inclusions = Farmer”s pox (Milker”s nodules/orf) + Individual necrotic keratocytes, lymphocytes, and vacuolar alteration along the de…

Histologic Diagnosis of Inflammatory Skin Diseases

Study By Disease

…iz #263) Nodular vasculitis (Quiz #780) Norwegian (keratotic) scabies (Quiz #109) Nummular dermatitis (Quiz #60) Nummular dermatitis (Quiz #242) Nummular dermatitis (Quiz #289) Nummular dermatitis (Quiz #398) Nummular dermatitis (Quiz #401) Nummular…

Histologic Diagnosis of Inflammatory Skin Diseases

Parasitic infestations

…cercaria and in gnathostomiasis. In a few instances, such as scabies and pediculosis, the parasites reside in, and on, human skin. Once larvae of nematodes have entered human skin, they do not mature into the adult form; they die where they reside,…

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

…hat is called pseudolymphoma in one instance could be nodular scabies, in another circumstance an expression of borreliosis, and in a third the response to a bite of a tick. That being the case, an effort should be made earnestly, always, to avoid th…

Histologic Diagnosis of Inflammatory Skin Diseases

Selection of the Site

…he skin, e.g., dermatitis herpetiformis, nummular dermatitis, scabies, Grover’s disease, and eosinophilic folliculitis, are exquisitely pruritic, scratching is an inevitable consequence, and signs of excoriation are nearly invariable. Excoriati…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…ce of the “bite” of an insect; the female mite of scabies may induce nodules of lymphocytes and eosinophils (so-called nodular scabies) and the bite of a tick may bring into being a dense nodular mixed-cell infiltrate of lymphocytes, hist…