Histologic Diagnosis of Inflammatory Skin Diseases

Leukocytoclastic vasculitis

Leukocytoclastic vasculitis Synonyms Leukocytoclastic angiitis Allergic vasculitis Hypersensitivity angiitis Hypersensitivity vasculitis Anaphylactoid purpura Immune complex vasculitis Purpura rheumatica Presentation stereotypical Age and sex Any ag…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Urticarial Vasculitis?

…protean by but a single type of lesion, e.g., “palpable purpura.” Nonetheless, dermatologists throughout the world use the term palpable purpura as a synonym for leukocytoclastic vasculitis (see the chapter “Palpable Purpura?&#8221…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Mucha-Habermann Disease a Lymphocytic Vasculitis?

…are seen clinically to be purpuric. Because the term palpable purpura is used wrongly by dermatologists as a synonym for small-vessel vasculitis (the lichenoid purpura of Gougerot and Blum, as well as a hematoma, are palpable purpuras devoid of vasc…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Necrotizing Vasculitis?

…enon or is it simply a synonym for leukocytoclastic (allergic) vasculitis (and scors of equivalents for that particular type f vasculitis, among those being Henoch-Sch?nlein and Gougerot-Ruiter types, small-vessel expression of periarteritis nodosa,…

Histologic Diagnosis of Inflammatory Skin Diseases

Septic vasculitis

…the infiltrate. Only venules are involved in leukocytoclastic vasculitis, whereas arterioles also are affected in septic vasculitis. Laboratory confirmation Chronic gonococcemia is proved by studies using immunofluorescence that permit identificat…

Differential Diagnosis in Dermatopathology

Nodular vasculitis vs. Subcutaneous polyarteritis nodosa

An inflammatory process, but not a vasculitis, that involves the legs especially with purpuric macules and subtle papules (Schamberg’s disease), lichenoid papules (lichenoid purpura of Gougerot-Blum), and scaly papules (eczematid-like purpura

Therapeutic Strategies in Dermatology

Urticaria: Key Points

Key Points Urticaria is a very common disease with a lifetime prevalence of approximately 20%. Individual lesions of urticaria typically present for less than 24 hours; persistence of a lesion greater than 24 hours is suggestive of a different diag…

Therapeutic Strategies in Dermatology

Borreliosis (Lyme Disease): Key Points

Key Points Infection with various Borrelia species causes borreliosis, which may have cutaneous and systemic manifestations. This infection is transmitted through bites of the Ixodes species of ticks. Early Lyme disease (erythema chronicum migrans…

Therapeutic Strategies in Dermatology

Lupus: Key Points

Key Points Lupus is a disease that presents across a broad spectrum of cutaneous and systemic manifestations. It may be cutaneous-only or systemic with cutaneous manifestations; some patients with systemic lupus do not have cutaneous involvement. D…

Therapeutic Strategies in Dermatology

Erysipelas/Cellulitis: Key Points

Key Points Erysipelas and cellulitis are infections of the dermis and subcutaneous layers of the skin that are rapidly progressive and are often accompanied by systemic signs, such as fever, leukocytosis, and elevated markers of systemic inflammat…