Search Results for: schonlein-henoch purpura vasculitis

Therapeutic Strategies in Dermatology

Lupus: Key Points

…mbination with systemic symptoms. Non-specific skin signs of systemic lupus include chilblains (pernio), livedo reticularis, vasculitis, and other (non-oral) ulcerations. Cutaneous lupus erythematosus (CLE) may be divided into four subtypes: discoid…

Therapeutic Strategies in Dermatology

Pernio/Chilblains: Key Points

…those patients should undergo an evaluation for possible chilblain lupus erythematosus. The presence of angulated, retiform purpura, or nonblanching sharply angled distal lesions, may prompt a consideration of a systemic thromboembolic disease,…

Therapeutic Strategies in Dermatology

Pernio/Chilblains: Treatment

…other systemic symptoms should undergo a thorough review of systems and targeted laboratory workup. The presence of retiform purpura or nonblanching purpuric lesions should prompt consideration for a thrombotic process such as cryoglobulinemia or…

Therapeutic Strategies in Dermatology

Leukocytoclastic Vasculitis: Treatment

…uce a remission then maintenance with lower toxicity agents. When to refer to a dermatologist When the diagnosis of palpable purpura is not clear. For skin biopsy of lesions to confirm the diagnosis. A biopsy for direct immunofluorescence (which…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lymphocytic Vasculitis?

…recognized for what it is by features clinical and findings histopathologic. The quintessential example of leukocytoclastic vasculitis is Henoch-Sch?nlein purpura; that of septic vasculitis, gonococcemia; and that of livedo vasculitis, atrophie…

Histologic Diagnosis of Inflammatory Skin Diseases

Leukocytoclastic vasculitis

…AN, Mihm MC Jr, Magro CM. Cutaneous vasculitis: a review. J Cutan Pathol 2003;30:161-73. Davin JC, Weening JJ. Diagnosis of HenochSchonlein purpura: renal or skin biopsy? Pediatr Nephrol 2003;18(12):1201-3. Epub 2003 Sep 16. Frost FA, Heenan PJ….

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Urticarial Vasculitis?

…e terms for all manifestations morphologic that appear at every stage in the evolution and devolution of it, e.g., vesicular vasculitis, pustular vasculitis, and ulcerated vasculitis. But those expressions of leukocytoclastic vasculitis are not…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Palpable Purpura?

…egregious as employing “palpable purpura” as a synonym for leukocytoclastic vasculitis. “Leukocytoclastic vasculitis (palpable purpura) represents an activated complement-induced inflammation of the small dermal vessels, chiefly…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Mucha-Habermann Disease a Lymphocytic Vasculitis?

…known etiology. Much evidence suggests that it is of infectious origin, possibly viral, with the production of a lymphocytic vasculitis or perivasculitis.” Gibson LE, Perry HO. Papulosquamous eruptions and exfoliative dermatitis. In: Moschella…