Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

Lichen planus Synonyms Lichen ruber planus Lichen ruber Presentation stereotypical Age and sex More common in women, especially young and middle-aged adults Distribution of lesions Flexor surface of forearms and wrists, but no site is exempt. Occu…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…rment type of congenital melanocytic nevus, an epidermal nevus like that known as ichthyosis hystrix, and a connective tissue nevus like a shagreen “patch.” Figure 3.27 Plaque. PROLIFERATION [L. proles (offspring) + ferre (to bear)]: A…

Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

…he newly formed phagolysosome, azurophilic granules being more likely to send their contents into phagosomes, whereas specific granules are more likely to discharge their contents extracellularly. Neutrophils function chiefly as phagocytes, but, as m…

Histologic Diagnosis of Inflammatory Skin Diseases

Hair Follicles

…numbers are interspersed among matrical cells in the bulb, few melanocytes are found along the course of the stem and the isthmus; in the infundibulum, melanocytes are disposed in a manner like that of surface epidermis. The growth of hair is cyclica…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Reticular Erythematous Mucinosis?

“Since it was not possible to relate these findings to any known syndrome, a combination of the main signs, reticular erythema and mucinosis, was used to name this entity REM syndrome.” Steigleder GK, Gartmann H, Linker U. REM syndrome…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

In this section, algorithms used to reach specific diagnosis are predicated on “nonspecific” findings recognized best at higher magnification. Other changes requisite for specific diagnoses, i.e., denominators that are essential, then ar…