Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…loped Superficial perivascular infiltrate of lymphocytes Bandlike infiltrate of lymphocytes across the upper part of the dermis, obscuring the dermoepidermal junction Vacuolar alteration along the junction Melanophages in variable number in the lich…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…ic process, those abscesses going under designations eponymic like Munro’s microabscess and spongiform pustule of Kogoj. Minuscule abscesses in eccrine units, designated neutrophilic eccrine hidradenitis, are a pattern that does not in itself c…

Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

…seborrheic keratosis, especially in the form of lichen planus-like keratosis, and a particular melanocytic nevus in the form of halo nevus) are associated with dense infiltrates of inflammatory cells, lymphocytes in particular. The term “inflam…

Histologic Diagnosis of Inflammatory Skin Diseases

Hair Follicles

…ibular and surface epidermis) and of trichohyalin granules (unlike the circumstance in the inner sheath). Just as epidermal keratocytes incorporate melanosomes by clipping off the ends of dendrites of melanocytes by a mechanism termed apocopation, ma…

Dermatology Practical & Conceptual

Spitz and Reed nevi: acquired or congenital?

…or subcutis [1,4,18,19]. In contrast to congenital nevi, the melanocytes of Clark nevi are usually monomorphous and small with an oval shape [1]. From a dermatoscopic point of view, acquired melanocytic nevi like Clark’s frequently exhibit a m…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…ed intracellular edema of keratocytes that may result in a netlike pattern of epidermis necrotic invariably. Click image to enlarge. + Individual necrotic keratocytes, lymphocytes, and vacuolar alteration along the dermoepidermal interface, and a per…