Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Keratosis Lichenoides Chronica?

…iffuse eruption characterized by papules, nodules, and keloid-like streaks disposed symmetrically in vertical rows parallel to the long axis of the neck and of the extremities. The linear lesions converged on the flexural aspect of the elbow and dive…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…ic process, those abscesses going under designations eponymic like Munro’s microabscess and spongiform pustule of Kogoj. Minuscule abscesses in eccrine units, designated neutrophilic eccrine hidradenitis, are a pattern that does not in itself c…

Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

…seborrheic keratosis, especially in the form of lichen planus-like keratosis, and a particular melanocytic nevus in the form of halo nevus) are associated with dense infiltrates of inflammatory cells, lymphocytes in particular. The term “inflam…

Histologic Diagnosis of Inflammatory Skin Diseases

Hair Follicles

…ibular and surface epidermis) and of trichohyalin granules (unlike the circumstance in the inner sheath). Just as epidermal keratocytes incorporate melanosomes by clipping off the ends of dendrites of melanocytes by a mechanism termed apocopation, ma…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…ed intracellular edema of keratocytes that may result in a netlike pattern of epidermis necrotic invariably. Click image to enlarge. + Individual necrotic keratocytes, lymphocytes, and vacuolar alteration along the dermoepidermal interface, and a per…

Dermatology Practical & Conceptual

Spitz and Reed nevi: acquired or congenital?

…or subcutis [1,4,18,19]. In contrast to congenital nevi, the melanocytes of Clark nevi are usually monomorphous and small with an oval shape [1]. From a dermatoscopic point of view, acquired melanocytic nevi like Clark’s frequently exhibit a m…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Reticular Erythematous Mucinosis?

…ticular erythematous mucinosis Synonyms. REM syndrome, plaque-like cutaneous mucinosis This syndrome comprises areas of reticular erythema on the trunk with a mucinous and round cell infiltrate in the dermis, and is frequently called the REM syndrome…