Therapeutic Strategies in Dermatology

Herpes Zoster & Varicella: Treatment

…for treatment with intravenous acyclovir. Pitfalls Secondary staphylococcal infection of varicella is common, and may be easily overlooked. Reye’s syndrome may follow varicella, especially in children in whom aspirin is used as an antipyretic…

Therapeutic Strategies in Dermatology

Vascular Birthmarks: Key Points

…are benign, however, in rare cases a PWS is associated with a syndrome with extracutaneous manifestations. Anatomic location of the PWS can be helpful to raise suspicion for such syndromes. For example, those involving the V1 distribution on the fac…

Therapeutic Strategies in Dermatology

Venous Stasis: Treatment

Treatment Stasis dermatitis First-line therapy: The first-line therapy for stasis dermatitis includes control of edema, if possible, and use of an anti-inflammatory topical medication such as a medium potency topical corticosteroid. Stasis dermati…

Histologic Diagnosis of Inflammatory Skin Diseases

Staphylococcal scalded skin syndrome

Staphylococcal scalded skin syndrome Synonyms Staphylococcal Lyell syndrome Dermatitis exfoliativa neonatorum Ritter disease Ritter von Rittershain-Lyell’s disease SSSS Staphylococcal toxic epidermal necrolysis Presentation stereotypical Age a…

Therapeutic Strategies in Dermatology

Darier’s Disease: Key Points

…om defects in calcium regulation in keratinocytes. The classic skin manifestation is an eruption of hyperkeratotic papules, typically in a seborrheic distribution. Characteristic nail and mucous membrane involvement is common. Superinfection of the s…

Therapeutic Strategies in Dermatology

Erythema Multiforme: Key Points

…ording to some authors, may be synonymous with Stevens-Johnson syndrome (SJS) and entails a more severe clinical syndrome with more atypical target lesions and pronounced mucosal involvement at two anatomic sites. EM major occurs in association with…

Histologic Diagnosis of Inflammatory Skin Diseases

Staphylococcal scalded skin syndrome

An inflammatory process expressed clinically by markedly edematous acuminate papules and edematous plaques situated mostly on the face, upper part of the trunk, and arms, especially the hands, and often accompanied by fever and leukocytosis. It may…

Therapeutic Strategies in Dermatology

Viral Exanthems: Initial Evaluation

…cella Pityriasis rosea Gianotti-Crosti syndrome Gianotti-Crosti syndrome is a non-specific viral eruption marked by monomorphic, lichenoid papules or papulovesicles especially on the face and extensor surfaces of extremities….

Therapeutic Strategies in Dermatology

Darier’s Disease: Clinical Case

…ast clinical evaluation Diagnosis: favor Darier’s disease with staphylococcal superinfection Skin cultures (bacterial, candidal, and herpes simplex viral culture) are obtained. The patient is empirically started on doxycycline 100 mg b.i.d. for 10 da…