Therapeutic Strategies in Dermatology

Melanoma: Key Points

…metastasis† c: In transit metastases/satellites without metastatic nodes N3 4+ metastatic nodes, or matted nodes, or in transit metastases/satellites with metastatic nodes M Site Serum LDH M0 No distant metastases NA M1a Distant skin, su…

Therapeutic Strategies in Dermatology

Photosensitivity Dermatoses: Overview

…protected areas; lose its seasonal variation; occur even when the inducing photosensitizer has been stopped; and have a broader wavelength of reactivity. This end stage may also demonstrate histologic features resembling cutaneous T cell lymphoma (so…

Histologic Diagnosis of Inflammatory Skin Diseases

Subcutaneous T-cell lymphoma

Subcutaneous T-cell lymphoma Synonyms Subcutaneous panniculitis-like lymphoma Presentation stereotypical Age and sex Mostly women in the third and fourth decades of life Distribution of lesions Extremities, trunk, face, neck, and breasts Arrangement

Differential Diagnosis in Dermatopathology

"Pseudolymphoma," B-cell type vs. Malignant lymphoma, B-cell type

type usually occurs as a solitary, rapidly growing tumor. Most of the neoplastic lymphocytes express the CD30 antigen. Panniculitis-like T-cell lymphoma is a distinct type derived from activated cytotoxic T-cells and characterized by plaques and sub…

Histologic Diagnosis of Inflammatory Skin Diseases

Subcutaneous T-cell lymphoma

type usually occurs as a solitary, rapidly growing tumor. Most of the neoplastic lymphocytes express the CD30 antigen. Panniculitis-like T-cell lymphoma is a distinct type derived from activated cytotoxic T-cells and characterized by plaques and sub…

A Clinical Atlas of 101 Common Skin Diseases

Lymphomatoid Papulosis

A distinctive type of CD 30 lymphoma characterized by the presence mostly of papules, some of them purpuric, that may ulcerate and heal with a scar, and by lesions that tend to come and go for years, eventually disappearing entirely or, on occasion,…

A Clinical Atlas of 101 Common Skin Diseases

Mycosis Fungoides

A systemic lymphoma of T-lymphocytes that manifests itself first in the skin as macules and then patches that often are scaly. Most people with the disease have only scaly macules and patches for a lifetime, but some patients may develop papules, pl…

Therapeutic Strategies in Dermatology

Dermatitis Herpetiformis: Key Points

…or systemic corticosteroids are of little value in DH. In addition, there are other autoimmune conditions associated with DH, most commonly hypothyroidism, as well as an increased risk of non-Hodgkin lymphoma, specifically bowel-associated T cell lym…

Therapeutic Strategies in Dermatology

Dermatitis Herpetiformis: Treatment

…gnosis of dermatitis herpetiformis should be reevaluated in patients who do not respond to appropriately administered sulfone therapy, as a rapid response is almost universal. Patients with dermatitis herpetiformis are at increased risk to develop ly…