Search Results for: systematized darier\'s disease

Therapeutic Strategies in Dermatology

Kaposi’s Sarcoma

An inflammatory process expressed clinically by markedly edematous acuminate papules and edematous plaques situated mostly on the face, upper part of the trunk, and arms, especially the hands, and often accompanied by fever and leukocytosis. It may…

Therapeutic Strategies in Dermatology

Sweet’s Syndrome (Acute Febrile Neutrophil Dermatosis)

An inflammatory process expressed clinically by markedly edematous acuminate papules and edematous plaques situated mostly on the face, upper part of the trunk, and arms, especially the hands, and often accompanied by fever and leukocytosis. It may…

Therapeutic Strategies in Dermatology

Sarcoidosis: Key Points

…ase, which is protean in its presentations but most commonly presents as papules, plaques, lupus pernio, or scar- or tattoo-associated lesions. Introduction Sarcoidosis is a complex multisystem inflammatory disease characterized by noncaseating…

Therapeutic Strategies in Dermatology

Kaposi’s Sarcoma: Overview

…KS) results from endothelial cell proliferation caused by infection with human herpesvirus 8 and occurs in four settings: classic KS, African (endemic) KS, immunosuppressive-associated KS, and AIDS-associated KS. The therapy of each form is

Therapeutic Strategies in Dermatology

Darier’s Disease: Treatment

…he starting dose is 0.2-0.3 mg/kg/day, with gradual escalation of the dose to the therapeutic range of 0.5-1 mg/kg/day. Successful use of alitretinoin in Dariers disease has recently been reported. Topical tretinoin 0.025% gel or 0.1% cream before…

Therapeutic Strategies in Dermatology

Dermatomyositis: Key Points

…h also frequently affects the muscles. Dermatomyositis can be a sign of internal malignancy, with 20% of patients having an associated cancer (ovarian cancer risk, in particular, is elevated). Patients require thorough evaluation for extracutaneous

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

Overview Langerhans cell histiocytoses (Class I histiocytosis) are a group of disorders most common in childhood due to the accumulation or proliferation of a clonal population of cells bearing the phenotype of a Langerhans cell that has been…

Therapeutic Strategies in Dermatology

Darier’s Disease: Key Points

…ant inheritance causing abnormalities of keratinization stemming from defects in calcium regulation in keratinocytes. The classic skin manifestation is an eruption of hyperkeratotic papules, typically in a seborrheic distribution. Characteristic…

Therapeutic Strategies in Dermatology

Darier’s Disease: References

References Abe M, Inoue C, Yokoyama Y, Ishikawa O. (2011). Successful treatment of Dariers disease with adapalene gel, Ped Derm, 28:197-198. Frezzini C, Cedro M, Leao JC, Porter S. (2006). Darier disease affecting the gingival and oral mucosal…

Therapeutic Strategies in Dermatology

Hailey-Hailey Disease: Key Points

…tly inherited genodermatosis caused by dysregulation of calcium hemostasis in the keratinocyte that leads to acantholysis (loss of cell-cell adhesion) in the epidermis. Clinically, it manifests with macerated, eroded plaques primarily in the…