Search Results for: systematized darier\'s disease

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

Overview Langerhans cell histiocytoses (Class I histiocytosis) are a group of disorders most common in childhood due to the accumulation or proliferation of a clonal population of cells bearing the phenotype of a Langerhans cell that has been…

Therapeutic Strategies in Dermatology

Darier’s Disease: Key Points

…ant inheritance causing abnormalities of keratinization stemming from defects in calcium regulation in keratinocytes. The classic skin manifestation is an eruption of hyperkeratotic papules, typically in a seborrheic distribution. Characteristic…

Therapeutic Strategies in Dermatology

Darier’s Disease: References

References Abe M, Inoue C, Yokoyama Y, Ishikawa O. (2011). Successful treatment of Dariers disease with adapalene gel, Ped Derm, 28:197-198. Frezzini C, Cedro M, Leao JC, Porter S. (2006). Darier disease affecting the gingival and oral mucosal…

Therapeutic Strategies in Dermatology

Hailey-Hailey Disease: Key Points

…tly inherited genodermatosis caused by dysregulation of calcium hemostasis in the keratinocyte that leads to acantholysis (loss of cell-cell adhesion) in the epidermis. Clinically, it manifests with macerated, eroded plaques primarily in the…

Therapeutic Strategies in Dermatology

Darier’s Disease: Clinical Case

s on the neck, upper chest Strong family history of Dariers disease Review of systems is notable only for recent fevers in association with worsening rash Presents for management of increasing erythema, crusting on the retroauricular neck, trunk,…

Therapeutic Strategies in Dermatology

Urticaria Pigmentosa / Mastocytosis: Key Points

…occur at any age, and may involve the skin, or affect internal organs including the bone marrow and liver/spleen/lymphatic tissues Urticaria pigmentosa is a form of cutaneous mastocytosis most common in childhood, characterized by brown papules,…

A Clinical Atlas of 101 Common Skin Diseases

Preface

…triking varieties. This method is new, and will be attended with many advantages…. ” In his book, Willan was the first to classify skin diseases systematically, according to different appearances of their individual lesionssuch as macules, papules,…

Therapeutic Strategies in Dermatology

Candidiasis: Key Points

…ogenital mucosal sites. Predisposing factors include obesity, diabetes, antibiotic or corticosteroid treatments, immunosuppression, removable prostheses, and chronic or frequent exposure to moisture including saliva, fecal and urinary incontinence….

A Clinical Atlas of 101 Common Skin Diseases

Epidermal Nevi

Epidermal nevi are hamartomas in which the epidermis is abnormal, being hyperkeratotic, and in which lesions are aligned along Blaschko’s lines.

Therapeutic Strategies in Dermatology

Aphthous Ulcers (Recurrent Aphthous Stomatitis, Canker Sore): Key Points

Key Points Recurrent aphthous ulcers are the most common oral ulcerative ailment, which classically appear as shallow, round or oval ulcers with an inflammatory edge and a faint pseudomembrane. Diagnosis may be made by history and physical exam…