Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Urticarial Vasculitis?

…ogy, 7th ed. Oxford: Blackwell Science, 2004:47.23. Cutaneous vasculitis, by definition, is small-vessel vasculitis. Large vessels, i.e., arteries and veins, are not found in the skin, but in septa of the subcutaneous fat. Small-vessel vasculitis ca…

Histologic Diagnosis of Inflammatory Skin Diseases

Leukocytoclastic vasculitis

Leukocytoclastic vasculitis Synonyms Leukocytoclastic angiitis Allergic vasculitis Hypersensitivity angiitis Hypersensitivity vasculitis Anaphylactoid purpura Immune complex vasculitis Purpura rheumatica Presentation stereotypical Age and sex Any ag…

Histologic Diagnosis of Inflammatory Skin Diseases

Livedo vasculitis

…t not by European ones. In any event, it is devoid of signs of vasculitis. Stasis changes are accompanied by other signs of venous insufficiency, such as varicose veins and pigmentary changes, but not by evidence of vasculitis. Findings histopatholo…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Mucha-Habermann Disease a Lymphocytic Vasculitis?

…nstances, the cells are neutrophils, e.g., in leukocytoclastic vasculitis, septic vasculitis, and livedo vasculitis. Rarely, lymphocytes monopolize the infiltrate that accompanies changes of small-vessel vasculitis. It cannot be emphasized too strong…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Necrotizing Vasculitis?

…lin Pathol 1952;22:777–90. “Cutaneous necrotizing vasculitis is an inflammatory process that involves vessels of all sizes …. The sequence of pathologic events in vasculitis is best illustrated in necrotizing venulitis of the super…

Histologic Diagnosis of Inflammatory Skin Diseases

Septic vasculitis

…the infiltrate. Only venules are involved in leukocytoclastic vasculitis, whereas arterioles also are affected in septic vasculitis. Laboratory confirmation Chronic gonococcemia is proved by studies using immunofluorescence that permit identificat…

Differential Diagnosis in Dermatopathology

Erythema nodosum vs. Nodular vasculitis

An arteritis in the subcutaneous fat manifested clinically at first by one or more red nodules that, in time, become ulcerated and heal with scars, usually on the posterior aspect of the legs of short, thick-legged women. No cause is usually found,…

Differential Diagnosis in Dermatopathology

Nodular vasculitis vs. Subcutaneous polyarteritis nodosa

An arteritis in the subcutaneous fat manifested clinically at first by one or more red nodules that, in time, become ulcerated and heal with scars, usually on the posterior aspect of the legs of short, thick-legged women. No cause is usually found,…

Histologic Diagnosis of Inflammatory Skin Diseases

Nodular vasculitis

…itself. Cause and mechanism Both are unknown. Comment Nodular vasculitis, at its zenith, is nodular clinically and a vasculitis of a large muscle-containing vessel histopathologically. The affected artery is situated in a septum in the subcutaneous…

Histologic Diagnosis of Inflammatory Skin Diseases

Nodular vasculitis

An arteritis in the subcutaneous fat manifested clinically at first by one or more red nodules that, in time, become ulcerated and heal with scars, usually on the posterior aspect of the legs of short, thick-legged women. No cause is usually found,…