Therapeutic Strategies in Dermatology

Vascular Birthmarks: Clinical Cases

…is: port-wine stain (PWS) No eyelid involvement (makes Sturge-Weber less likely) Natural history of PWS discussed Treatment options reviewed: no treatment, pulse-dye laser Family chooses to pursue pulse-dye laser Follow-up evaluation Lesion appeara…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eosinophilic Cellulitis (Wells’ Syndrome)?

…7:46–56. “Eosinophilic cellulitis (Wells’ syndrome) is an inflammatory dermatosis characterized by marked eosinophilic infiltrates. Drugs and various infections are recognized causes of eosinophilic cellulitis.” Hirsch K, Lu…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Follicular Degeneration Syndrome?

…kin. 9th ed. 2005; 493-4. The “follicular degeneration syndrome,” described by Sperling and Sau in 1992 and elaborated on by Sperling et al. in 1994, is said to represent a “clinically and histologically distinct form of scarring a…

Histologic Diagnosis of Inflammatory Skin Diseases

Staphylococcal scalded skin syndrome

Staphylococcal scalded skin syndrome Synonyms Staphylococcal Lyell syndrome Dermatitis exfoliativa neonatorum Ritter disease Ritter von Rittershain-Lyell’s disease SSSS Staphylococcal toxic epidermal necrolysis Presentation stereotypical Age a…

Histologic Diagnosis of Inflammatory Skin Diseases

Toxic shock syndrome

Toxic shock syndrome Synonyms TSS Presentation stereotypical Age and sex Women using super-absorbent vaginal tampons especially, but possible in both sexes consequent to any infection by pathogenic bacteria, particularly Staphylococcus aureus, inclu…

Histologic Diagnosis of Inflammatory Skin Diseases

Sweet’s syndrome

Sweet’s syndrome Synonyms Acute febrile neutrophilic dermatosis Presentation stereotypical Age and sex Middle-aged persons, more often women than men Distribution of lesions Upper and lower extremities, neck, and face. Sometimes limited to dor…

Differential Diagnosis in Dermatopathology

Erythema multiforme vs. Toxic shock syndrome

An inflammatory process expressed clinically by markedly edematous acuminate papules and edematous plaques situated mostly on the face, upper part of the trunk, and arms, especially the hands, and often accompanied by fever and leukocytosis. It may…