Study By Disease

Study By Disease

…gely resolved (Quiz #92) Verrucae vulgares (Quiz #704) Viral exanthem (Quiz #760) Viral exanthem (Quiz #821) Viral exanthem (Quiz #822) Vitiligo (Quiz #502) Wegener’s granulomatosis (Quiz #890) X-linked ichthyosis (Quiz #501) Xanthogranuloma (Q…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Ichthyosis vulgaris X-linked ichthyosis 1. Cornified layer thickened, but less than half the thickness of the viable epidermis 1. Cornified layer thickened and often at least half the thickness of the viable epidermis 2. Lamellate and basket-w…

Differential Diagnosis in Dermatopathology

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Ichthyosis vulgaris X-linked ichthyosis

Histologic Diagnosis of Inflammatory Skin Diseases

Grover’s disease

…acantholytic dermatosis Presentation stereotypical Age and sex Middle-aged and elderly adults, hardly ever younger than age 40 years and usually over age 60 years; white men mostly Distribution of lesions Widespread, but especially the trunk and les…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Reactive Perforating Collagenosis?

“A case is presented exhibiting an unusual reaction of the skin to superficial trauma. In response to minor trauma, certain changes take place within the papillary layer of the corium characterized by affinity of the connective tissue for he…

Histologic Diagnosis of Inflammatory Skin Diseases

Nerves

…avel along the course of the superficial and deep vascular plexuses, whence derives the term neurovascular plexuses. Figure 1.82 Unmyelinated cutaneous nerve endings transmit sensations of touch, pressure, temperature, pain, and itch to the centra…

Histologic Diagnosis of Inflammatory Skin Diseases

Ground Substance

…of a long-chain, aminated polysaccharide (glycosaminoglycan) linked covalently to a polypeptide. The terms mucopolysaccharide, mucosubstance, mucin, and proteoglycan are used interchangeably to refer to the entire polysaccharide-polypeptide complex….

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Fibrosing Dermatitis

…assault coming either from outside or from inside the skin. External injuries to skin generally take the form of wounds, i.e., erosions and/or ulcerations (Fig. 5.351 A&B) inflicted by fingernails as they are employed like talons in the act of a…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Acquired Epidermolysis Bullosa?

…erage” case of epidermolysis bullosa acquisita may not exist or is at least poorly defined due to the small number of cases accepted as authentic epidermolysis bullosa acquisita.” Woodley DT, Gammon WR. Epidermolysis bullosa acquisita: an…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Atopic Dermatitis?

…opic eczema,’ ‘hay fever eczema,’ ‘flexural eczema,’ unfortunately frequently just ‘eczema.’” Sulzberger MB, Spain WC, Sammis F, et al. Studies in hypersensitiveness in certain dermatoses. J Allergy 1932;3:42…