Search Results for: xanthogranuloma

Histologic Diagnosis of Inflammatory Skin Diseases

Necrobiosis lipoidica

…alisades of necrobiosis lipoidica. Despite the similarity in nomenclature, necrobiosis lipoidica is unrelated to necrobiotic xanthogranuloma. More often than not, necrobiosis lipoidica is a manifestation of diabetes, whereas necrobiotic…

Histologic Diagnosis of Inflammatory Skin Diseases

Xanthomas

…rae). The gray hue of the cytoplasm of histiocytes of leprosy is caused by the presence of myriad acid-fast bacilli (globi). Xanthogranuloma is a type of xanthoma typified by a dense diffuse infiltrate that, when developed fully, houses…

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

…n of collagen in necrobiosis lipoidica, extensive degeneration of collagen and necrosis of inflammatory cells in necrobiotic xanthogranuloma, and fibrin in abundance in rheumatoid nodules. Because of the marked differences in findings…

Histologic Diagnosis of Inflammatory Skin Diseases

Urticaria pigmentosa

…nosis histopathologic One or but a few lesions of juvenile urticaria pigmentosa misdiagnosed clinically as those of juvenile xanthogranuloma: Denominators in common: Yellowish smooth-surfaced papules and nodules are present. Features…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…and lymphocytes in a nodular infiltrate (fully developed), and all of those findings with the addition of fibrosis (late) = Xanthogranuloma + Foamy histiocytes with gray cytoplasm (“globi”) in a nodular infiltrate = Leprosy,…

Dermatoscopy: What is your diagnosis?

Dermatoscopy: What is your diagnosis?

…of Dermatology Practical and Conceptual. Answer to April 2012 quiz The correct answer to the quiz in the April 2012 issue is xanthogranuloma. Please see article 3 of this issue of Dermatology Practical and Conceptual for a detailed description of…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…iable in lobular panniculitides as a consequence of necrosis of adipocytes and are a finding, consistently, in xanthomas and xanthogranulomas. Multinucleate histiocytes, as well as mononuclear ones, may be found in a granuloma, and they have been…

Histologic Diagnosis of Inflammatory Skin Diseases

Study By Disease

…) Viral exanthem (Quiz #822) Vitiligo (Quiz #502) Wegener’s granulomatosis (Quiz #890) X-linked ichthyosis (Quiz #501) Xanthogranuloma (Quiz #106) Xanthogranuloma (Quiz #735) Zitelli’s nevus (superficial and “deep” congenital…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 11.24.1A: Nodular dermatosis + 11.24.1B: Foamy histiocytes in a papule = Xanthoma A xanthoma differs from a xanthogranuloma by being made up of a nearly pure population of foamy histiocytes, practically none of which are multinucleate, and…