Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Pernio, Perniosis, Lupus Pernio, Chilblain, and Chilblain Lupus?

“Eleven out of 17 presented with chilblain LE after the development of facial discoid LE and the delay varied from 1 to 14 years (mean 5.9 years). . . . Three patients had chilblains and bad circulation before the onset of LE. The sites of th…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Pseudopelade?

…poid, is characterized by acute folliculitis with inflammation of the dermis in the zone of involvement.” Brocq L. Recherches sur l”alopecie atrophiante, vari?t? pseudopelade [Research about atrophic alopecia, pseudopelade variant]. Ann…

Histologic Diagnosis of Inflammatory Skin Diseases

Lymphocytoma cutis

…large pleomorphic nuclei and abundant cytoplasm. Usually, some of those lymphocytes are in mitosis and others are binucleate and multinucleate. In the variant marked by a mix of cells, there may be small lymphocytes, plasma cells, eosinophils, and ne…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…looning, intraepidermal vesiculation, or neutrophils in mounds of parakeratosis; in fact, spongiosis in slight and the thickened cornified layer is devoid of inflammatory cells. 10.66.14A: Vesicular dermatitis, ostensibly subepidermal, and peri…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Perforating Diseases?

…ating are unrelated to one another. The exact status nosologic of Kyrle’s disease never will be known because Kyrle did not make clear the attributes morphologic or the cause of it. His patients were diabetic. So-called perforating folliculitis…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema nodosum leprosum

…lar panniculitis, focal at first and then diffuse Patchy zones of extensive fat necrosis Foam cells scattered in fat lobules In fibrous septa of the subcutaneous fat, fibrin in the wall of some small vessels and thrombi in the lumen of others Sparse…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Malignant Spitz Nevus?

…mitotic rate and mitosis deep within the lesion. There is more cellular pleomorphism, less maturation in depth and less cohesion of cells than in the usual Spitz nevus.” Weedon D, Strutton G. Skin Pathology. 2nd ed. New York: Churchill-Livings…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…tigo contagiosa Only the presence of bacteria in the cytoplasm of some neutrophils enables a diagnosis of impetigo to be made with surety. Otherwise, the findings histopathologic are indistinguishable from those of pemphigus foliaceus, including the…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Necrotizing Vasculitis?

…itic process, venules themselves are not necrotic. Only living cells can become necrotic and endothelial cells of those venules show no signs of necrosis; they, themselves, do not seem to be affected. Collagen in the wall of vessels involved cannot b…