Search Results for: dermatitis herpetiformis-like drug eruption

Histologic Diagnosis of Inflammatory Skin Diseases

Precepts Adjunctive to the Algorithmic Method

…nfused with a variety of superficial perivascular and interstitial dermatitides that range from papular eruption of HIV to a drug eruption. Other neoplastic simulators of inflammatory diseases are lymphomatoid papulosis, adult T-cell…

Differential Diagnosis in Dermatopathology

Urticarial reaction to an arthropod assault vs. Urtica

Psoriasis is a chronic, immune-mediated polygenic skin disorder affecting approximately 2% of the population. The pathogenesis of psoriasis features an interplay between adaptive and innate immunity centered on interleukin 23 and T-helper 17 cells…

Differential Diagnosis in Dermatopathology


…n a number of conditions other that brought about by the “bite” of an arthropod, such as is the case commonly in dermatitis herpetiformis and bullous pemphigoid, and uncommonly in pemphigus vulgaris and polymorphous light eruption….

Histologic Diagnosis of Inflammatory Skin Diseases

Blister secondary to hypoxemia and local pressure

…beneath the epidermis, as is the case for most blisters that develop secondary to hypoxia and local pressure. Ingestion of a drug alone also cannot be responsible for the condition; lesions may appear in the absence of any intake of a drug. Comment…

Histologic Diagnosis of Inflammatory Skin Diseases

Bullous pemphigoid

…ight spongiosis; those changes may be impossible to distinguish at times from some urticarial lesions of bullous pemphigoid. Dermatitis herpetiformis is diagnosed on the basis of collections of neutrophils at the tip of dermal papillae and in…

Histologic Diagnosis of Inflammatory Skin Diseases

Epidermolysis bullosa simplex

…rficialis. Differential diagnosis clinical Bullous impetigo consists of blisters that, in time, become pustular and crusted. Dermatitis herpetiformis usually is confined to the extensor surface of extremities. Linear IgA dermatosis has a…

Histologic Diagnosis of Inflammatory Skin Diseases

Acquired epidermolysis bullosa

…ny infundibular cysts that form in the process of re-epithelization beneath blisters. Differential diagnosis histopathologic Dermatitis herpetiformis and linear IgA dermatosis resemble closely the inflammatory type of acquired epidermolysis bullosa….

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Urticarial Vasculitis?

…es besides leukocytoclastic vasculitis, e.g., insect “bites,” bullous pemphigoid, herpes gestationis, dermatitis herpetiformis, and allergic contact dermatitis. Although urticarial papules are common to all of those disorders, each of…

Histologic Diagnosis of Inflammatory Skin Diseases

Dermoepithelial Interface

…of any of the components results in a variety of diseases, among them blistering disorders such as porphyria cutanea tarda, dermatitis herpetiformis, and bullous pemphigoid. Figure 1.71 A. Schematic representation of the dermoepidermal junction as…