Histologic Diagnosis of Inflammatory Skin Diseases

Pernio

…nd the infiltrate is superficial only. A particular expression of lupus erythematosus on the hands and feet of young women, usually without discernible edema in the papillary dermis probably is a variant of pernio. Laboratory confirmation None exist…

Histologic Diagnosis of Inflammatory Skin Diseases

Lymphocytoma cutis

…large pleomorphic nuclei and abundant cytoplasm. Usually, some of those lymphocytes are in mitosis and others are binucleate and multinucleate. In the variant marked by a mix of cells, there may be small lymphocytes, plasma cells, eosinophils, and ne…

Differential Diagnosis in Dermatopathology

Apocrine mixed tumor vs. Eccrine mixed tumor

A benign neoplasm of apocrine ductal nature within the upper half of the dermis that manifests itself clinically as tiny, smooth, skin-colored, round or oblong papules that usually are situated in periorbital skin, but may be seen on other sites, su…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Diabetic Dermopathy?

…athy, nor do we observe any sign of vasculitis. In their study of changes histopathologic of diabetic dermopathy, Binkley, Gerolds, and Stoughton found … thick-walled capillaries in the upper dermis. The endothelial cells are prominent. The adv…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Dandruff a Disease?

….” The stratum disjunctum represents histologic evidence of exfoliation of cornified cells from normal skin. In actuality, dandruff is simply the visible gross expression of the “stratum disjunctum.” It is constituted of orthokerato…