Search Results for: clear-cell variant of squamous-cell carcinoma

Histologic Diagnosis of Inflammatory Skin Diseases

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…rmal spinous layer in association with incipient acantholytic cells = Impetigo contagiosa Only the presence of bacteria in the cytoplasm of some neutrophils enables a diagnosis of impetigo to be made with surety. Otherwise, the findings histopatholog…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Malignant Spitz Nevus?

“A rare malignant variant of the Spitz naevus has been reported which features a higher mitotic rate and subcutaneous invasion. It may metastasize to the regional lymph nodes but not beyond.” Weedon D, Stratton G. Malignant melanoma pat…

Histologic Diagnosis of Inflammatory Skin Diseases

Hailey-Hailey disease

…as thought by them and by others in the ensuing years to be a variant of pemphigus vulgaris. The reasons for that misinterpretation were the flaccidity of the blisters clinically and the acantholytic cells in the epidermis histopathologically. Despit…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lymphocytic Infiltration of Jessner?

…ys, around vessels and/or appendages. The infiltrates consist of lymphocytes, mostly small ones, and usually a few histiocytes and plasma cells.” Jessner M, Kanof NB, Orfuss AJ. Lymphocytic infiltration of the skin. Arch Dermatol 1953;68:447&#8…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Dandruff a Disease?

…” The stratum disjunctum represents histologic evidence of exfoliation of cornified cells from normal skin. In actuality, dandruff is simply the visible gross expression of the “stratum disjunctum.” It is constituted of orthokeratot…