Dermatology Practical & Conceptual

When all you have is a dermatoscope—start looking at the nails

…d with the formation of nail alterations. However, only a few drugs are regularly responsible for toxic effects on the nail matrix, the nail bed or the periungual skin [23]. These drugs predominantly include retinoids and chemotherapeutics like docet…

Histologic Diagnosis of Inflammatory Skin Diseases

Lymphocytoma cutis

…of tattoos Simulators of T-cell lymphoma, e.g., Lymphomatoid drug eruption
Lymphomatoid contact dermatitis
Lichenoid purpura of Gougerot and Blum
Various inflammatory diseases episodically, as dissimilar as psoriasis and dermatophytosis Findings hi…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema nodosum

…nodosum Synonyms Erythema contusiforme Erythema contusiformis Dermatitis contusiformis Erythema nouesux Presentation stereotypical Age and sex Young adults, especially women Distribution of lesions Bilateral and symmetrical over the pretibial and lat…

Histologic Diagnosis of Inflammatory Skin Diseases

Leprosy

…f lymphocytes that spare cutaneous nerves. Polymorphous light eruption differs from indeterminate leprosy by the presence, often, of notable edema in the papillary dermis. The tumid variant of discoid lupus erythematosus differs from indeterminate le…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…folliculitis, but an infundibulitis. 10.27.3A: Pustular dermatitis, infundibular, mixed-cell + 10.27.3B: Eosinophils predominate over neutrophils = Eosinophilic pustular folliculitis So-called eosinophilic pustular folliculitis likely is a…

Histologic Diagnosis of Inflammatory Skin Diseases

Pruritic urticarial papules and plaques of pregnancy

…tends to be slight and does not eventuate in vesiculation, unlike the situation in some responses to the assault of arthropods. The differential diagnosis of pruritic urticarial papules and plaques of pregnancy also includes a drug eruption of one t…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…es in diseases that erupt, such as erythema multiforme, fixed drug eruption, and Mucha-Habermann disease, are situated in the lower part of the epidermis. 10.53.3A: Vesicular dermatitis, intraepidermal, ballooned and spongiotic + 10.53.3B:…

Histologic Diagnosis of Inflammatory Skin Diseases

Nerves

…ssociated with itching; among the most notorious of these are dermatitis herpetiformis, Grover’s disease, and scabies. Scratching is thought to relieve itching by disturbing the rhythm of afferent impulses that travel toward the central nervous…