Search Results for: dermatitis herpetiformis-like drug eruption

Dermatology Practical & Conceptual

Author Guidelines / Dermatology Practical & Conceptual

…e most easily identifiable conflicts of interest and the most likely to undermine the credibility of the journal, the authors, and of science itself. However, conflicts can occur for other reasons, such as personal relationships, academic competition…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema nodosum

…nodosum Synonyms Erythema contusiforme Erythema contusiformis Dermatitis contusiformis Erythema nouesux Presentation stereotypical Age and sex Young adults, especially women Distribution of lesions Bilateral and symmetrical over the pretibial and lat…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…not a folliculitis, but an infundibulitis. 10.27.3A: Pustular dermatitis, infundibular, mixed-cell + 10.27.3B: Eosinophils predominate over neutrophils = Eosinophilic pustular folliculitis So-called eosinophilic pustular folliculitis likely is a supp…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…es in diseases that erupt, such as erythema multiforme, fixed drug eruption, and Mucha-Habermann disease, are situated in the lower part of the epidermis. 10.53.3A: Vesicular dermatitis, intraepidermal, ballooned and spongiotic + 10.53.3B: Strikingly…

Histologic Diagnosis of Inflammatory Skin Diseases

Pruritic urticarial papules and plaques of pregnancy

…tends to be slight and does not eventuate in vesiculation, unlike the situation in some responses to the assault of arthropods. The differential diagnosis of pruritic urticarial papules and plaques of pregnancy also includes a drug eruption of one t…

Histologic Diagnosis of Inflammatory Skin Diseases

Leprosy

…f lymphocytes that spare cutaneous nerves. Polymorphous light eruption differs from indeterminate leprosy by the presence, often, of notable edema in the papillary dermis. The tumid variant of discoid lupus erythematosus differs from indeterminate le…

Histologic Diagnosis of Inflammatory Skin Diseases

Fixation of the Specimen

…s diseases, e.g., bullous pemphigoid, pemphigus vulgaris, and dermatitis herpetiformis. When diagnosis with precision of a vesiculobullous disease is the goal, a biopsy specimen for direct immunofluorescence must be taken from skin contiguous to a ne…

Histologic Diagnosis of Inflammatory Skin Diseases

Nerves

…ssociated with itching; among the most notorious of these are dermatitis herpetiformis, Grover’s disease, and scabies. Scratching is thought to relieve itching by disturbing the rhythm of afferent impulses that travel toward the central nervous…