Differential Diagnosis in Dermatopathology

Herpes simplex vs. Vaccinia

An inflammatory disease of genetic nature that begins with red macules that quickly become nonscaly papules that in turn become scaly papules and plaques. If the process becomes widespread, an erythroderma results, and if it is accelerated, pustules…

Differential Diagnosis in Dermatopathology

Discussions

…cy for vesicles to form rapidly and in clusters, as they do in dermatitis herpetiformis and herpes gestationis, neither of which has been shown to be viral in cause. When herpes simplex or zoster/varicella occurs in patients with other skin diseases…

Differential Diagnosis in Dermatopathology

Images

Dermatitis herpetiformis Bullous pemphigoid…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Dermatitis herpetiformis Bullous pemphigoid 1. Subepidermal blister that contains neutrophils mostly; eosinophils in variable number, present, too, about 72 hours after onset 1. Subepidermal blister that contains eosinophils mostly; neutrophils…