Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Common Baldness—an Inflammatory Disease?

…nflammatory process.” Abell E. Pathology of male pattern alopecia. Arch Dermatol 1984;120:1607–8. “These lesions were localized both in and outside of are as affected by alopecia androgenetica and were associated with mild pruritu…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Pseudopelade?

…as meant, when introduced, to convey a sense for simulation of alopecia areata. During the past 75 years, however, pseudopelade has come to be used as a term generic for permanent scarring alopecia, a phenomenon very different from alopecia areata wh…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Anagen Effluvium?

…uvium, several authors have included a hodgepodge of unrelated alopecias, for example, hair loss induced by chemotherapy, genetic disorders (monilethrix), infections of the follicle (tinea capitis), alopecia areata, and various so-called scarring alo…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…3.2B: Lymphocytes around matrical cells of a follicular bulb = Alopecia areata ┬áThe changes pictured, although rather paltry, are sufficient to make a diagnosis definitively of alopecia areata or one of the analogues of it, to wit, alopecia totalis a…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…ntend that it refers to any permanent (“scarring”) alopecia, chronic discoid lupus erythematosus among others. Perhaps the greatest challenge in differential diagnosis of lichen planopilaris is traction alopecia, which also presents itsel…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…he result being production of a leonine face in some patients. Alopecia areata, at times, may be reminiscent clinically of alopecia mucinosa on a scalp, but it is neither erythematous nor scaly, and is devoid of any accentuation of infundibula, unlik…

Histologic Diagnosis of Inflammatory Skin Diseases

Telogen effluvium

…pelage Differential diagnosis clinical Androgenetic (common) alopecia develops slowly and progressively; persists for a lifetime, and affects principally the frontoparietal and vertex regions. Traction alopecia affects the frontal hairline and pa…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

Error: Abortive is an accurate modifier of particular pathologic processes, e.g., abortive dermatofibroma, abortive morphea, and abortive T-cell lymphoma. Reason: The idea itself is abortive! For example, what is called “abortive T-cell lympho…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Telogen Effluvium—An Inflammatory Disease?

…of the cycle (i.e., telogen) and that may result in observable alopecia. The reason for discernible alopecia is that so many follicles, many more than usual, have gone into telogen, with inevitable and invariable loss of their club hairs. Just as the…