Therapeutic Strategies in Dermatology

Pyoderma Gangrenosum: Treatment

Treatment First-line therapy: The first-line therapy for pyoderma gangrenosum is comprised of two key elements: controlling inflammation and optimizing wound care. Inflammatory control may require systemic immunosuppression and/or the use of multip…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Perivascular Dermatitis

See Figs. 5.16 A&B, 5.17 A&B, 5.18 A&B, 5.19 A&B, 5.20 A&B, 5.21 A&B, and 5.22 A&B Figure 5.16 A. Perivascular dermatitis, perivascular only, superficial. B. Perivascular dermatitis, perivascular only, superficial and…

Histologic Diagnosis of Inflammatory Skin Diseases

Pellagra

Pellagra Synonyms Niacin deficiency Presentation stereotypical Age and sex Any age and either sex; more common in developing countries in which malnutrition is prevalent, but may be seen in industrialized countries where factors for malnutrition, e….

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Churg-Strauss Granuloma and Allergic Granulomatosis?

…called attention to the condition in an abstract published in 1949 and they expanded on it in 1951 in an article about “allergic granulomatosis, allergic angiitis, and periarteritis nodosa.” Their concept of allergic granulomatosis, as e…

Dermatology Practical & Conceptual

Regression of nevi in a melanoma patient treated with interferon

…ray granularity which in general represent regression (Figures 1, 2). In order to further analyze the lesions, confocal microscopy was performed (VivaScope 1500, Lucid Inc, Rochester, New York). Instrumentation and acquisition procedures have been de…

Dermatology Practical & Conceptual

Langerhans cell histiocytosis-a case report

…comparison to his high school peers. Actually, his height was 1.70 m, being at the 25th percentile according to the CDC 2000 growth chart (height versus age percentile graphic). Figure 1. (A) Slightly elevated erythematous papules covered by yell…

Histologic Diagnosis of Inflammatory Skin Diseases

Traumatic fat necrosis

….g., oral mucous membranes secondary to sucking on a popsicle. Alpha-1-antitrypsin deficiency panniculitis is characterized by tender plaques, nodules, and/or ulcers on the trunk and extremities. The lesions look as if they have been induced artifici…