Differential Diagnosis in Dermatopathology

Discussions

…tation. In contrast, lichen planus does not eventuate often in atrophy, but resolves usually with hyperpigmentation only. When lesions of lichen planus proceed to atrophy they appear as hyperpigmented macules that are depressed slightly below the sur…

Differential Diagnosis in Dermatopathology

Atrophic lichen planus vs. Atrophic discoid lupus erythematosus

A granulomatous inflammatory process characterized clinically by patches that become yellowish plaques and that in time resolve with atrophy and telangiectases. The condition usually occurs in persons with diabetes….

Dermatology Practical & Conceptual

Linear atrophoderma of Moulin: a case report and review of the literature

…connective tissue texture, and the clinical impression of skin atrophy was attributed to atrophy of the subcutaneous tissue [1]. Up to now there have been 30 reported cases of linear atrophoderma of Moulin [2-22]. In 2005, Ang et al mentioned that ma…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

Mycosis fungoides Synonyms Cutaneous T-cell lymphoma Presentation stereotypical Age and Sex Adults usually, although children may be affected. Males preponderant. Distribution of lesions Often widespread, but sometimes localized to a single patch or…

Dermatology Practical & Conceptual

Hyperkeratotic necrobiosis lipoidica

Case report A 56-year-old Caucasian male with a history of uncontrolled diabetes mellitus and multiple other comorbidities was evaluated for slowly expanding plaques of his right lower leg, left forearm and left dorsal hand that had been present for…

Histologic Diagnosis of Inflammatory Skin Diseases

Lipodystrophy

Lipodystrophy Synonyms Lipoatrophy Wucher atrophy Presentation stereotypical Age and sex Females, first decade of life Distribution of lesions Upper half of body in the “partial” expression of the process and widespread in the “t…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Atrophie Blanche?

“In any event, it is a special form of cutaneous atrophy in its presentation, a real idiopathic malady, i.e., if you do not wish to attribute it to syphilis, [and] we designate it ‘atrophie blanche.’ … Histologic examination…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

Lichen planus Synonyms Lichen ruber planus Lichen ruber Presentation stereotypical Age and sex More common in women, especially young and middle-aged adults Distribution of lesions Flexor surface of forearms and wrists, but no site is exempt. Occu…

Differential Diagnosis in Dermatopathology

Discussions

…all the more visible by an epidermis that has become thinned. Atrophy of that type is characterized histopathologically by a striking loss of dermal papillae and a consequent loss of epidermal rete ridges. Such atrophy (whether in the form of lichen…