Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…on that has counterparts clinical and histopathologic. Error: Atrophy of skin in general, i.e., in all atrophodermas, results entirely from loss of elastic fibers. Reason: Although loss of elastic fibers contributes greatly to the appearance of some…

Differential Diagnosis in Dermatopathology

Atrophic lichen planus vs. Atrophic discoid lupus erythematosus

…expression of a small lesion of anetoderma is “macular atrophy” secondary to destructive changes of acne vulgaris, and of a large lesion of anetoderma is stria atrophicans. Striae are linear lesions that at first are elevated and plethor…

Differential Diagnosis in Dermatopathology

Discussions

…two very different diseases whose lesions longstanding end in atrophy, they can be differentiated histopathologically by an exceedingly thin epidermis often in discoid lupus erythematosus, overtly wedge-shaped hypergranulosis in repeatable manner in…

Dermatology Practical & Conceptual

Hyperkeratotic necrobiosis lipoidica

…examination revealed annular waxy brown plaques with central atrophy and a lilac colored advancing edge located on the right posterior-lateral calf measuring 5 x 4 cm (Figure 1), left dorsal hand 5 x 3.5 cm and left forearm 11 x 9 cm. Interestingly,…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…t is called parakeratosis variegata, and when it is joined by atrophy, hyper-, and hypopigmentation, and telangiectases it is referred to as poikiloderma vasculare atrophicans. Different manifestations of large-plaque parapsoriasis sometimes occur to…

Histologic Diagnosis of Inflammatory Skin Diseases

Lipodystrophy

Lipodystrophy Synonyms Lipoatrophy Wucher atrophy Presentation stereotypical Age and sex Females, first decade of life Distribution of lesions Upper half of body in the “partial” expression of the process and widespread in the “t…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…20;burned out” lichen planus, resolving as it does with atrophy. Annular lichen planus is seen most often in Africans and African-Americans. So-called actinic lichen planus (lichen planus subtropicus, lichen planus tropicus, lichen planus actin…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Atrophie Blanche?

“In any event, it is a special form of cutaneous atrophy in its presentation, a real idiopathic malady, i.e., if you do not wish to attribute it to syphilis, [and] we designate it ‘atrophie blanche.’ … Histologic examination…