Search Results for: atrophy

Differential Diagnosis in Dermatopathology

Atrophic lichen planus vs. Atrophic discoid lupus erythematosus

An inflammatory disease of children and adults that tends to involve skin and skeletal muscle mostly, the findings in the skin being patches with the color of heliotrope, especially in the periocular region. The disease manifests itself as…

Differential Diagnosis in Dermatopathology

Discussions

…a late one. Furthermore, in an early lesion, there is no fibrosis in the upper part of the dermis and no signs clinically of atrophy clinically. Atrophy in lichen planus and in discoid lupus erythematosus is of the superficial type characterized…

Linear atrophoderma of Moulin: a case report and review of the literature

Linear atrophoderma of Moulin: a case report and review of the literature

…stinct pigment incontinence, no inflammation or alteration of connective tissue texture, and the clinical impression of skin atrophy was attributed to atrophy of the subcutaneous tissue [1]. Up to now there have been 30 reported cases of linear…

Hyperkeratotic necrobiosis lipoidica

Hyperkeratotic necrobiosis lipoidica

…x 9 cm. Interestingly, a 5.5 x 4.5 cm plaque on the right anterior lower leg exhibited central hyperkeratosis as opposed to atrophy (Figure 2). A punch biopsy of the atrophic plaque on the left forearm was performed, which revealed granulomatous…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…ble from the erythroderma of Sézary’s syndrome. Findings histopathologic “Early” patch (devoid of signs of atrophy clinically) Superficial perivascular and variably interstitial infiltrate of lymphocytes Subtle patchy lichenoid…

Histologic Diagnosis of Inflammatory Skin Diseases

Lipodystrophy

…scles may appear to be hypertrophic and veins may seem to be prominent. Differential diagnosis histopathologic Localized fat atrophy secondary to local injections of corticosteroid or insulin is typified by decrease in the size of adipocytes that…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…rete ridges as a consequence of the effects of products of lymphocytes, the papillary dermis being somewhat fibrotic and the atrophy being accounted for by the loss of tissue. Lichen planopilaris begins as punctate macules equidistant from one…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Atrophie Blanche?

…r Dermatol Syphilol 1929;36:867–68. “Although previously considered to be due to a vasculitis, atrophie blanche (white atrophy) is best regarded as a manifestation of a vasculopathy in which occlusion of small dermal vessels by fibrin thrombi…

Histologic Diagnosis of Inflammatory Skin Diseases

Lupus erythematosus

…discoid lupus erythematosus, thereby precluding any changes residual typical of lesions longstanding of discoid type, e.g., atrophy and pigmentary alterations. Neonatal lupus erythematosus simply is lupus erythematosus in a newborn or infant in…