Therapeutic Strategies in Dermatology

Grover’s Disease / Transient Acantholytic Dermatosis: Key Points

…emitropical climates, with fever, and after hospitalization or bed rest. Immunosuppression may increase the risk of developing TAD, as it is seen in patients with HIV infection, in leukemia, and in patients recently receiving bone marrow transplants….

Therapeutic Strategies in Dermatology

Sweet’s Syndrome (Acute Febrile Neutrophil Dermatosis): Treatment

…phenolate mofetil SSKI Pitfalls Sweet’s syndrome may be associated with hematologic malignancy, classically acute myelogenous leukemia, and may present during a leukemic or preleukemic state. These patients are frequently anemic. Because us…

Dermatology Practical & Conceptual

Balloon cell melanoma in primary care practice: a case report

…suspect that it was melanocytic. The lesion was reported as a balloon cell melanoma, Clark level 4, Breslow thickness 2 mm with a mitotic index of 4 per square mm. This is an extremely rare melanoma subtype. Author DW has encountered only two cases…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Langerhans’ Cell Granulomatosis?

…s granulomatous processes are devoid of the granules. It could be inferred that histiocytes produce the granules only in certain proliferative conditions (for instance, in HX) but this would imply that intraepidermal Langerhans’ cells [LC] or L…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lymphocytic Vasculitis?

…was no evidence for an association with systemic disease. Skin biopsy of lesions showed a lymphocytic vasculitis with red blood cell extravasation.” Sellick GS, Coleman RJ, Webb EL, Chow J, Bevan S, Rosbotham JL, Houlston RS. Dominantly inheri…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Cutaneous T-cell Lymphoma?

…(CTCL), also known as mycosis fungoides, consists of malignant cells that resemble mature T cells. Vargo N. Cutaneous malignancies: KA, CTCL, and KS. Dermatol Nurs. 2006;18(3):270,277. New designations for diseases do not always represent an advanc…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Basal-Cell Carcinoma Common in Nevus Sebaceus?

“Nevus sebaceus may be ‘programmed’ for or susceptible to the eventual development of a variety of neoplasms that generally occur in adulthood. The most common of these is basal cell carcinoma, which develops in 5% to 7% of the l…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lymphocytic Infiltration of Jessner?

…ythematosus when the reticular dermis houses formidable mucin, but neither eosinophils or plasma cells. In our view, lymphocytic infiltration of Jessner and Kanof simply is tumid lupus erythematosus. “Although many authors believe Jessner̵…

Dermatology Practical & Conceptual

Langerhans cell histiocytosis-a case report

…mbling the format of a kidney and others reminiscent of coffee beans. Numerous intermingling eosinophils were present. The diagnosis of Langerhans cell histiocytosis was then rendered and confirmed by positive immunostaining of neoplastic cells for a…