Search Results for: ballooning

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…pigmentosa Vesicles in prurigo pigmentosa may come into being by virtue of extensive spongiosis, early in the process, or by ballooning later. Neutrophils are the first inflammatory cells to arrive in the epidermis and are joined there a day or so…

Histologic Diagnosis of Inflammatory Skin Diseases

Irritant contact dermatitis/Phototoxic dermatitis

…ptotic cells.” Neutrophils are attracted chemotactically to necrotic keratocytes. The blister that results from marked ballooning of keratocytes forms first in the epidermis, but, if the reaction is intense sufficiently, it becomes…

Differential Diagnosis in Dermatopathology

Discussions

…iculation. That is not the case for Mucha-Habermann disease; almost always the intraepidermal blister comes about because of ballooning. In both diseases, ballooning tends to progress to vesiculation affiliated with reticular alteration which is…

Differential Diagnosis in Dermatopathology

Discussions

…is characterized by spongiosis with little, if any, ballooning, in contrast to the situation in phototoxic dermatitis where ballooning of keratocytes is prominent and spongiosis is not. Severe ballooning in phototoxic dermatitis, accompanied as it…

Histologic Diagnosis of Inflammatory Skin Diseases

Limitations of the Algorithmic Method

…selected be that of “interface dermatitis, vacuolar type,” of “spongiotic dermatitis,” or of “ballooning dermatitis”? If inflammatory cells are distributed lightly, but surely, along the dermoepidermal junction…

Histologic Diagnosis of Inflammatory Skin Diseases

Drug eruptions

…erivascular dermatitis, to wit, perivascular only; perivascular and interstitial; interface, vacuolar, interface, lichenoid; ballooning; spongiotic, and psoriasiform. Of these, interface dermatitis is the most common, and psoriasiform dermatitis is…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…t infiltrate of neutrophils mostly + 10.11.4C + 10.11.4D = Burn The blister shown began in the epidermis as a consequence of ballooning that led to epidermal necrosis; on rupture, the intraepidermal blister became subepidermal, too. Neutrophils are…

Histologic Diagnosis of Inflammatory Skin Diseases

Measles

…s Slight spongiosis Slight ballooning Few individual necrotic keratocytes in the spinous zone, especially in the vicinity of ballooning Few multinucleate epithelial giant cells in foci of spongiosis and ballooning Slight focal parakeratosis…