Histologic Diagnosis of Inflammatory Skin Diseases

Thrombophlebitis

Thrombophlebitis Presentation stereotypical Age and sex Women most commonly Distribution of lesions Localized to the lower extremities usually Arrangement of lesions Linear often, i.e., along the course of a vein Individual lesions Cord sometimes in…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.38.1A: Pustular dermatitis, infundibular + 10.38.1B: A hair containing hyphae in an abscess = Suppurative infundibulitis of dermatophytic cause (Majocchi’s granuloma) The hair was spewed into the dermis when an infundibul…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Epidemic of Melanoma?

“Malignant melanoma of the skin is a major cancer in the young, working population, second in prevalence only to cancers of the testis in males in the 30-49-year-old range. Moreover, there is a recent increase in the incidence and mortality o…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Wide and Deep Excision for Melanoma?

“Widths of excision as much as 100 mm from the edge of the lesion have been advocated and most surgeons have practiced wide excision with a 50-mm margin area without anatomical limitations.” McLeod GRC. Malignant melanoma: primary trea…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Mycosis Fungoides—Increasing in Incidence?

“Mycosis fungoides does appear to be increasing in frequency more rapidly than lymphoma in general.” Weinstock MA. Epidemiology of mycosis fungoides. Semin Dermatol 1994;13(3):154–59. “The incidence [of mycosis fungoides…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Scleroderma?

“Scleroderma is a chronic disease of unknown cause that affects the microvasculature and loose connective tissue and is characterized by fibrosis and obliteration of vessels in the skin, lungs, gastrointestinal tract, kidneys and heart. It m…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Sclerotic Fibroma?

“Nine biopsies revealed a distinctive type of fibroma characterized by an organized pattern of interwoven fascicles of collagen bundles with a laminated or tortuous appearance, embedded in abundant mucin. A number of fibromas showed striking…