Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.17.1A: Nodular dermatitis, granulomatous + 10.17.1B: Collections of histiocytes enveloped by lymphocytes and plasma cells, and brown spores in a multinucleate macrophage = Chromomycosis In a fully developed lesion o…

Histologic Diagnosis of Inflammatory Skin Diseases

Histiocytosis X

Histiocytosis X Presentation stereotypical Age and sex Children, boys mostly, and also adults Distribution of lesions Localized or widespread Individual lesions Red papules, purpuric papules, erosions, and ulcers Course Protracted, if not treated; s…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Pityrosporum Folliculitis and Demodectic Folliculitis?

“We suggest that pityrosporum folliculitis may either be due to the predisposition of the host in the presence of the Pityrosporum organism, or the pathogenicity of certain strains of the Pityrosporum organism is capable of producing follicul…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.58.1A: Perivascular and interstitial dermatitis + 10.58.1B: Neutrophils and copious quantities of nuclear “dust” of neutrophils in association with many extravasated erythrocytes = Leukocytoclastic vasculitis, early…

Histologic Diagnosis of Inflammatory Skin Diseases

Tinea versicolor

Tinea versicolor Synonyms Pityriasis versicolor Dermatomycosis furfuracea Presentation stereotypical Age and sex Young adult men especially, but anyone can be affected Distribution of lesions Trunk particularly, but also the proximal aspect of the e…

Histologic Diagnosis of Inflammatory Skin Diseases

Acrodermatitis enteropathica

Acrodermatitis enteropathica Synonyms Zinc deficiency Presentation stereotypical Age and sex Infants of both sexes who suffer from an inherited deficiency of zinc; may occur in adults; characterized in infants by a triad of acral dermatitis, alopeci…

Differential Diagnosis in Dermatopathology

Leukokeratosis vs. Leukoplakia

An inflammatory disease caused by the yeast Candida albicans and manifested clinically as erythematous papules and pustules that may become confluent to form plaques in the case of the former and erosions in the case of the latter. The nail unit may…

Differential Diagnosis in Dermatopathology

Discussions

Leukokeratosis and leukoplakia are white, slightly elevated nonindurated lesions of the mucosae (especially of the mouth, but also of the vagina and other areas) that also have some attributes histopathologic in common, namely, hyperkeratosis, a thi…