Search Results for: cleft

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…umulated at the dermoepidermal junction as a product of the extraordinarily accelerated process that culminates in vesicles. Clefts cannot be seen clinically; blisters can be. Histopathologically, clefts in lichen planus seem to represent a…

Differential Diagnosis in Dermatopathology

Discussions

…s in general: vertical orientation often, sharp circumscription, smooth border, compression of enveloping connective tissue, clefts between compressed fibrous tissue and normal dermis or subcutaneous fat, tendency to “pop out” and…

Differential Diagnosis in Dermatopathology

Discussions

…tosis, which is a pattern distinctive of cutaneous epithelium, the acantholytic dyskeratotic cells appear above a suprabasal cleft, not in a suprabasal vesicle. In the pure Darier type of Grover’s disease, the findings are those of true focal…

Histologic Diagnosis of Inflammatory Skin Diseases

Fixed drug eruption

…illary dermis, sometimes marked Vacuolar alteration at the dermoepidermal junction; if extensive, eventuates in subepidermal clefts and subepidermal vesicles Marked spongiosis and ballooning; if ballooning extensive sufficiently, reticular…

A quiz from Manaus, Brazil

A quiz from Manaus, Brazil

…and a dilated entrapped follicle (H&E x40). [Copyright: ©2015 Miranda et al.] What is your diagnosis? Figure 2A. Stromal clefts and spindle cells in storiform and whorled fashions (H&E x100). [Copyright: ©2015 Miranda et al.]   Figure…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…and fat lobules is a patchy lymphocytic infiltrate, typical of morphea. 10.97.13A: Perivascular dermatitis and subepidermal cleft + 10.97.13B: Crowded thickened bundles of collagen in the upper part of the dermis, an infundibulum plugged by…

Differential Diagnosis in Dermatopathology

Dermatofibroma vs. Desmoplastic Spitz’s nevus

A genetically determined disorder in which numerous closely set keratotic papules are present on the skin, especially the trunk, in nail units, and on mucous membranes, particularly the palate, but also rarely in other parts of the gastrointestinal…