Search Results for: cleft

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…umulated at the dermoepidermal junction as a product of the extraordinarily accelerated process that culminates in vesicles. Clefts cannot be seen clinically; blisters can be. Histopathologically, clefts in lichen planus seem to represent a…

Differential Diagnosis in Dermatopathology

Discussions

…tosis, which is a pattern distinctive of cutaneous epithelium, the acantholytic dyskeratotic cells appear above a suprabasal cleft, not in a suprabasal vesicle. In the pure Darier type of Grover’s disease, the findings are those of true focal…

Differential Diagnosis in Dermatopathology

Discussions

…s in general: vertical orientation often, sharp circumscription, smooth border, compression of enveloping connective tissue, clefts between compressed fibrous tissue and normal dermis or subcutaneous fat, tendency to “pop out” and…

A quiz from Manaus, Brazil

A quiz from Manaus, Brazil

…and a dilated entrapped follicle (H&E x40). [Copyright: ©2015 Miranda et al.] What is your diagnosis? Figure 2A. Stromal clefts and spindle cells in storiform and whorled fashions (H&E x100). [Copyright: ©2015 Miranda et al.]   Figure…

Histologic Diagnosis of Inflammatory Skin Diseases

Fixed drug eruption

…illary dermis, sometimes marked Vacuolar alteration at the dermoepidermal junction; if extensive, eventuates in subepidermal clefts and subepidermal vesicles Marked spongiosis and ballooning; if ballooning extensive sufficiently, reticular…

Differential Diagnosis in Dermatopathology

Discussions

…ong fish-like tails, a shape that has prompted the comparison of clusters of those cells to “schools of fish.” A cleft often surrounds each of the distinctive polygonal melanocytes. When viewed by conventional microscopy, melanocytes of…