Histologic Diagnosis of Inflammatory Skin Diseases

Erythema elevatum diutinum

…attern at sites where previously there had been nodular and/or diffuse mixed-cell infiltrates. Diffuse, but sparse, infiltrate of neutrophils accompanied by nuclear “dust” of neutrophils throughout the zones of fibroplasia Scattered eosin…

Histologic Diagnosis of Inflammatory Skin Diseases

Lymphocytoma cutis

Lymphocytoma cutis Synonyms Pseudolymphoma Presentation stereotypical Age and sex Any age in both sexes Distribution of lesions Face and extremities especially Individual lesions Papules and nodules Course Weeks, months, and sometimes years; usually…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Verruciform Xanthoma?

“A relationship most likely exists between the verruciform appearance of the epithelium and the underlying foam cells. . . . One might suspect that epithelial breakdown, from some as yet unknown cause may secondarily elicit a foam-cell respo…

Histologic Diagnosis of Inflammatory Skin Diseases

Nephrogenic fibrosing dermopathy

…f an early stage of the disease. There they found a subtle but diffuse increase in the reticular dermis of spindle cells with ovoid basophilic nuclei. In sections of biopsy specimens obtained from lesional skin they noted a diffuse array throughout t…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Keratosis Lichenoides Chronica?

…ter. In the same article, Kaposi told of a child affected by a diffuse eruption of red nodules that were disposed both as solitary units and in confluence, and of gray-white squamous lesions. The face was livid diffusely and the color did not diminis…

Dermatology Practical & Conceptual

When all you have is a dermatoscope—start looking at the nails

…) Overview. (B) Dermatoscopy. The dermatoscopic view reveals a diffuse yellow-red discoloration of multiple nails indicative of an increased vascularization of the nail matrix and a diffuse transient extravasation of erythrocytes. Multiple dot-shaped…

Dermatology Practical & Conceptual

Blue nevus with a starburst pattern on dermoscopy

Abstract An 11-year-old girl presented to our department with a blue-gray papule approximately 4 mm in diameter. We suspected that it was a blue nevus or a pigmented Reed/Spitz nevus. On dermoscopic observation, the lesion showed homogeneous black-b…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…s. Histopathologically, it is seen to consist of a sparse, but diffuse, infiltrate of neutrophils mostly. Phlegmonous inflammation differs from suppurative inflammation, which also consists mostly of neutrophils, by displaying sparse polymorphs in di…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.7.1A: Diffuse dermatitis, mixed-cell + 10.7.1B: Proliferation of venules lined by plump endothelial cells, a sprinkling of neutrophils and nuclear “dust” of neutrophils, and clumps of granular violaceous material = B…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Perivascular Dermatitis

See Figs. 5.16 A&B, 5.17 A&B, 5.18 A&B, 5.19 A&B, 5.20 A&B, 5.21 A&B, and 5.22 A&B Figure 5.16 A. Perivascular dermatitis, perivascular only, superficial. B. Perivascular dermatitis, perivascular only, superficial and…