Histologic Diagnosis of Inflammatory Skin Diseases

Lymphocytoma cutis

Lymphocytoma cutis Synonyms Pseudolymphoma Presentation stereotypical Age and sex Any age in both sexes Distribution of lesions Face and extremities especially Individual lesions Papules and nodules Course Weeks, months, and sometimes years; usually…

Dermatology Practical & Conceptual

Nodules on the right ear

Case report A healthy 17-year-old boy with a one-year history of asymptomatic, slowly enlarging nodules affecting his right ear was seen. The patient’s past medical history was unremarkable, he was not immunosuppressed, he was not taking any d…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Keratosis Lichenoides Chronica?

…ter. In the same article, Kaposi told of a child affected by a diffuse eruption of red nodules that were disposed both as solitary units and in confluence, and of gray-white squamous lesions. The face was livid diffusely and the color did not diminis…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…s. Histopathologically, it is seen to consist of a sparse, but diffuse, infiltrate of neutrophils mostly. Phlegmonous inflammation differs from suppurative inflammation, which also consists mostly of neutrophils, by displaying sparse polymorphs in di…

Dermatology Practical & Conceptual

Blue nevus with a starburst pattern on dermoscopy

Abstract An 11-year-old girl presented to our department with a blue-gray papule approximately 4 mm in diameter. We suspected that it was a blue nevus or a pigmented Reed/Spitz nevus. On dermoscopic observation, the lesion showed homogeneous black-b…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Verruciform Xanthoma?

“A relationship most likely exists between the verruciform appearance of the epithelium and the underlying foam cells. . . . One might suspect that epithelial breakdown, from some as yet unknown cause may secondarily elicit a foam-cell respo…

Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

Neutrophils, eosinophils, lymphocytes, plasma cells, and histiocytes are called inflammatory cells because they enter tissue during the process of inflammation. A more exact designation for them is “cells of an inflammatory process”; the…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.7.1A: Diffuse dermatitis, mixed-cell + 10.7.1B: Proliferation of venules lined by plump endothelial cells, a sprinkling of neutrophils and nuclear “dust” of neutrophils, and clumps of granular violaceous material = B…

Histologic Diagnosis of Inflammatory Skin Diseases

Predominantly Intraepithelial Fluorescence

Intraepithelial, in this context, usually is synonymous with intraepidermal, both surface and infundibular, although in some instances, particularly pemphigus vulgaris, adnexal epithelium also may be affected. The prototype for intraepithelial fluor…