Histologic Diagnosis of Inflammatory Skin Diseases

Bullous pemphigoid

Bullous pemphigoid Synonyms Pemphigoid Presentation stereotypical Age and sex Onset usually in the seventh or eighth decade of life, but sometimes somewhat earlier, in both sexes; only rarely in young persons Distribution of lesions Inner aspects o…

Histologic Diagnosis of Inflammatory Skin Diseases

Advantages of the Algorithmic Method

By utilizing an algorithmic method based mostly on analysis of patterns formed by inflammatory cells, of alterations in epidermal and adnexal epithelium, and of the character of the inflammatory cells themselves, order can be brought to a subject ab…

Differential Diagnosis in Dermatopathology

Discussions

In a collagenous type of connective tissue nevus, known also as collagenoma, and in a lesion late in the course of morphea, abnormalities of connective tissue are observed mostly in the dermis. Bundles of collagen are thickened throughout the reticu…

Differential Diagnosis in Dermatopathology

Morphea, late stage vs. Collagenous nevus

A disease manifested chiefly in the skin by vesicles and bullae that appear on sites of trauma, especially the face and dorsa of the hands, often in conjunction with macular hyperpigmentation and hypertrichosis of a face and sclerodermoid changes on…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen sclerosus et atrophicus

Lichen sclerosus et atrophicus Synonyms Lichen sclerosis Lichen alba White spot disease Presentation stereotypical Age and sex Any age, but most common in middle-aged women Distribution of lesions Genitalia particularly, but also other sites such as…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

-oid?

“-oid (-oid) [eides, like]. A suffix signifying likeness or resemblance.” Bould G. The Practitioner’s Medical Dictionary. 3rd ed. Philadelphia, PA: P. Blakiston’s Son & Co., 1916:622. “-ode, -odes, -oid, -oides […

Differential Diagnosis in Dermatopathology

Images

Angiolymphoid hyperplasia with eosinophilia Angiosarcoma…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Angiolymphoid hyperplasia with eosinophilia Kimura’s disease 1. Does not usually resemble lymphoid tissue when viewed at scanning magnification 1. Resembles lymphoid tissue when viewed at scanning magnification 2. Few lymphoid follicles;…

Differential Diagnosis in Dermatopathology

Study By Disease

“Blue nevus” (Jadassohn-Tièche) (Quiz #360) “Blue nevus” (Jadassohn-Tièche) (Quiz #525) “Blue nevus” (Masson’s blue neuronevus) (Quiz #359) “Collagenous” nevus, papillary dermal type* (Quiz #11…