Search Results for: fibrin

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Urticarial Vasculitis?

…e., nuclear “dust” (leukocytoclasis). Nearly always, erythrocytes are extravasated among the inflammatory cells. Fibrin, however, is not present in the wall of venules in the urticarial stage of leukocytoclastic vasculitis; it appears…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema nodosum leprosum

…ecause on rare occasions careful scrutiny of sections of tissue from specimens of erythema nodosum leprosum does reveal some fibrin in the wall of small vessels and thrombi in some of their lumen. In most specimens, however, there are no signs of…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Necrobiosis?

…thelioid histiocytes. Rheumatoid nodule is a granulomatous panniculitis (and sometimes dermatitis) in which huge deposits of fibrin are surrounded by thin epithelioid histiocytes arrayed in a palisade. From the preceding brief descriptions, it is…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Hyalin?

…nosis also is a misnomer; that material is devoid of lipid. In the circumstances just cited, what is reputed to be hyalin is fibrin, necrotic keratocytes, degenerated erythrocytes, fibronectin, basement membrane material, and neutral…

Differential Diagnosis in Dermatopathology

Discussions

…of the paucity of inflammatory cells, they sometimes being absent altogether, but they differ from livedo vasculitis because fibrin cannot be discerned in the wall of vessels. Livedo vasculitis must be distinguished from livedo reticularis…

Differential Diagnosis in Dermatopathology

Discussions

…ous fat, whereas granuloma annulare does not. In subcutaneous granuloma annulare, vasculitis of small vessels in the form of fibrin in the wall of venules is present in the center of some palisades, yet the vasculitis in rheumatoid nodule,…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…reticular alteration + 10.99.5C + 10.99.5D = Septic vasculitis Unlike the situation in leukocytoclastic vasculitis in which fibrin is present in the wall of venules, in septic vasculitis thrombi are present in lumen of them. That occlusion results…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…et’s disease, this is not leukocytoclastic vasculitis because thrombi are present in the lumen of venules, rather than fibrin in the wall of them. 10.8.3A: Vesicular dermatitis, intraepidermal, ballooned + 10.8.3B: Neutrophils and eosinophils…

Histologic Diagnosis of Inflammatory Skin Diseases

Cat-scratch disease

…gal infection is characterized often by prominent scale-crust. Findings histopathologic Fully developed Zone of necrosis and fibrin in the upper part of the reticular dermis surrounded by a mantle of macrophages, lymphocytes, and plasma cells…