Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Metastasizing Dermatofibroma?

…n consists entirely of inflammatory cells, i.e., histiocytes, fibrocytes, and sometimes lymphocytes. At the outset, many erythrocytes are extravasated consequent to the effects of the initiating trauma, and products of them are ingested by macrophage…

Histologic Diagnosis of Inflammatory Skin Diseases

Scleromyxedema

…ndings histopathologic Fully developed Increase in number of fibrocytes in the dermis Increase in number of collagen bundles in the dermis, some arranged in whorls or in intersecting short fascicles Presence of mucin among bundles of collagen Diffe…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…us structures above the neoplasm as a rule 4. Numerous oval fibrocytes, histiocytes, and coarse bundles of collagen arranged haphazardly; interlacing fascicles episodically 4. Numerous oval, spindled, and wavy cells in company with fibrillary bundl…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…cinous 5. Mast cells increased slightly in loci mucinous 6. Fibrocytes increased slightly and scattered as solitary units in stroma, mucin-rich, mostly in the upper half of the dermis 6. Fibrocytes increased markedly in number with their long axis…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…hen tumble into the papillary dermis where they are coated by fibrocytes, the product being globules of amyloid. The globules in the upper part of the dermis are stained red by crystal violet. 11.3.2A: Perivascular dermatosis, superficial +…

Histologic Diagnosis of Inflammatory Skin Diseases

Acroangiodermatitis of Mali/Stewart-Bluefarb syndrome

…h thick walls and plump endothelial cells Increased number of fibrocytes in the region of the proliferated vessels; variable fibroplasia Extravasated erythrocytes and hemosiderin in the vicinity of the altered blood vessels Infiltrate of lymphocytes…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…e inclusions of cytomegalic disease are found most readily in fibrocytes, histiocytes, and endothelial cells. 10.16.3A: Ulcer with crust + 10.16.3B: Purple inclusions in nuclei of endothelial cells = Cytomegalic inclusion dise…