Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.9.1A: Perivascular and interstitial dermatitis + 10.9.1B: Lymphocytes, plasma cells, and eosinophils = Borreliosis In the United States, the findings pictured here are termed “erythema chronicum migrans” and are cons…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Dermatofibroma?

“Cutaneous fibroma Fibroma simplex Simple fibroma of the skin, as defined above, is a benign tumor, usually appearing solitary, on the upper part of the body and the extremities, which, mainly imbedded in the skin, is only rarely and little…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.37.1A: Pustular dermatitis, infundibular + 10.37.1B: Numerous Demodex folliculorum and squames in a zone of suppuration = Suppurative infundibulitis of unknown cause Demodex, Pityrosporum, bacteria, sebum, squames, and cornified…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Common Baldness—an Inflammatory Disease?

“The results also show that inflammation in MPA [male pattern alopecia] is a relatively consistent finding and that, although often insignificant, this frequently leads to an inflammatory folliculitis, perifollicular fibrosis, and unusually…

Differential Diagnosis in Dermatopathology

Atrophic lichen planus vs. Atrophic discoid lupus erythematosus

A red, often ulcerated, boggy papule that represents a hyperplasia of small cutaneous vessels which are “fed” by an arteriole in the subcutaneous fat, the lesion resulting consistently from external trauma, usually in the form of a punct…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Pustular Dermatitis

See Fig. 5.307 A&B. Figure 5.307 Pustular dermatitis. A. Infundibular. B. Surface epidermal. Although most pustules in skin are housed in infundibular epidermis (Fig. 5.308 A&B), many are lodged in surface epidermis (Fig. 5.309 A&B)….

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.20.1A: Nodular dermatitis, granulomatous + 10.20.1B: Numerous extravasated erythrocytes, siderophages, and fibrocytes = Dermatofibroma An important finding for diagnosis of a dermatofibroma such as this one is seen at the periph…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.96.1A: Fibrosing dermatitis + 10.96.1B: Plump fibrocytes, coarse bundles of collagen in haphazard array, and patchy infiltrate of iron-containing macrophages = Scar, very early  Innumerable macrophages replete with iron bear tes…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.94.1A: Infundibulitis, spongiotic, and peri-infundibulitis, granulomatous + 10.94.1B: Lymphocytes and plasma cells around collections of epithelioid histiocytes = Rosacea, papular  Spongiosis in an infundibulum is a finding comm…