Dermatology Practical & Conceptual

Langerhans cell histiocytosis-a case report

…e sampled for histopathologic examination and revealed a dense cellular infiltrate made up of mononuclear cells with conspicuous eosinophilic cytoplasm and large cleaved vesicular nucleus, some of them with shapes resembling the format of a kidney an…

Dermatology Practical & Conceptual

Saved by step sections: an unusual presentation of basal cell carcinoma

…pothesis. Patient: 21-year-old female with a superficial basal cell carcinoma in pubic region diagnosed after histological step sections and treated with topical imiquimod. Conclusions: Although very rare, basal cell carcinomas do occur in young pati…

Histologic Diagnosis of Inflammatory Skin Diseases

Subcutaneous T-cell lymphoma

…mis and subcutaneous fat. Histiocytosis X (Langerhans” cell histiocytosis) consists of a dense infiltrate of abnormal Langerhans” cells characterized by large, pale, reniform nuclei and abundant amphophilic cytoplasm, many eosinophils,…

Differential Diagnosis in Dermatopathology

Pale-cell acanthoma vs. Psoriasis, plaque expression

Noninflammatory scaly disorders in which polygonal gray or brown scales tend to be elevated at their periphery, causing them to appear to be separated from contiguous scales, findings that are seen in three conditions, namely, ichthyosis vulgaris (a…