Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Verruciform Xanthoma?

…he end stage of a verruca that involuted); an alteration in a hamartoma, e.g., an epidermal nevus; a repeated insult, e.g., blisters of recessive dystrophic epidermolysis bullosa; and a change in a long-established neoplasm, e.g., squamous-cell carci…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eccrine Neoplasms?

…duct proliferation Eccrine-centered nevus Eccrine angiomatous hamartoma Syringofibroadenoma or acrosyringeal nevus Comedo nevus of the palm, linear eccrine nevus with comedone, porokeratotic eccrine ostial nevus or porokeratotic eccrine duct and hair…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Myxoma?

…Williams & Wilkins, 1990:1020. “Lastly, neoplastic-hamartomatous cutaneous mucinosis include mucinous nevus, a benign hamartoma, and myxoma, which is a benign tumor to be differentiated from reactive cutaneous focal mucinosis.” Rong…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Epidermal Cyst and Epidermoid Cyst?

…20;decapitation secretion.” The cystic component of the hamartoma known as steatocystoma is lined by epithelium just like that of a sebaceous duct, namely, a thin epithelium that possesses a basal, spinous, subtly granular, and thin cornified l…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Infundibulo-folliculo-sebaceous cystic hamartoma Steatocystoma 1. Situated mostly in the dermis as a rule; sometimes also the subcutaneous fat 1. Situated in either the dermis or the subcutaneous fat, or both together 2. Cyst does not “p…

Differential Diagnosis in Dermatopathology

Images

Infundibulo-folliculo-sebaceous cystic hamartoma Steatocystoma…

Differential Diagnosis in Dermatopathology

Syringocystadenoma papilliferum vs. Hidradenoma papilliferum

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…

Differential Diagnosis in Dermatopathology

Discussions

…ngle specimen. The large nodular type is seen commonly in the hamartoma, nevus sebaceus. Often, the large nodules are pigmented heavily by melanin as a consequence of the activity of dendritic melanocytes housed within aggregations of neoplastic tric…

Differential Diagnosis in Dermatopathology

Discussions

…d malignant neoplasms that may arise within nevus sebaceus, a hamartoma marked by alterations of the dermis, the epidermis, and the epithelial structures of adnexa, as well at times of the subcutaneous fat. Clinically, it is relatively easy to suspec…