Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Epidermal Cyst and Epidermoid Cyst?

“Epidermoid cyst. Synonym: Sebaceous cyst, steatoma, epithelial cyst. Definition: A cyst containing keratin and its breakdown products, surrounded by an epidermoid wall.” Mackie RM. Epidermal skin tumors. In: Champion RH, Burton JL, Eb…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Myxoma?

“myxoma (milk – s ? m?) [myxo - + G. -oma, tumor]. A benign neoplasm derived from connective tissue, consisting chiefly of polyhedral and stellate cells that are loosely embedded in a soft mucoid matrix, thereby resembling primitive mes…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Infundibulo-folliculo-sebaceous cystic hamartoma Steatocystoma 1. Situated mostly in the dermis as a rule; sometimes also the subcutaneous fat 1. Situated in either the dermis or the subcutaneous fat, or both together 2. Cyst does not “p…

Differential Diagnosis in Dermatopathology

Images

Infundibulo-folliculo-sebaceous cystic hamartoma Steatocystoma…

Differential Diagnosis in Dermatopathology

Syringocystadenoma papilliferum vs. Hidradenoma papilliferum

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…

Differential Diagnosis in Dermatopathology

Discussions

Syringocystadenoma papilliferum and hidradenoma papilliferum are both apocrine papillated cystadenomas. Clinically, syringocystadenoma papilliferum appears at birth or in early childhood as a crusted, often weeping, verrucous plaque, usually on the…

Differential Diagnosis in Dermatopathology

Discussions

The small nodular types of trichoblastoma and of basal-cell carcinoma have many attributes histopathologic in common. For example, both are made up of nodules of follicular germinative cells, i.e., neoplastic trichoblasts, nodules are mostly small a…

Differential Diagnosis in Dermatopathology

Discussions

Porokeratotic epidermal nevus and inflammatory linear verrucous epidermal nevus have in common well-circumscribed loci of parakeratosis beneath which the granular zone is absent, alternation of zones of ortho- and parakeratosis, and an epidermis tha…