Histologic Diagnosis of Inflammatory Skin Diseases

Kimura’s disease

Kimura’s disease Synonyms Eosinophilic lymphofolliculitis Presentation stereotypical Age and sex Young men, especially Asians Distribution of lesions Head, neck, and trunk Individual lesions Firm nodules and tumors, some gigantic, above which…

Differential Diagnosis in Dermatopathology

Discussions

…tage of dermatofibroma also has been referred to as sclerosing hemangioma, a misnomer because it is not a hemangioma and early in the course of it never is sclerosing. A papule occurs on a lower extremity especially, particularly in women, and in tim…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Colors Stereotypical for Diseases Specific?

“The color of skin lesions varies as already stated. … White lesions are rare excepting in exfoliative diseases, the scales of which are white. They usually result from loss of pigment. White spot disease, morphea, some of the idiopathi…

Differential Diagnosis in Dermatopathology

Discussions

Despite the differences biologic between dermatofibroma (an inflammatory process) and desmoplastic (fibrosing, largely intradermal) Spitz’s nevus (a benign neoplastic process), the two conditions have many attributes morphologic in common. Bot…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Histiocytoses?

“The concept of grouping as related disorders those which feature proliferation of cytologically mature benign histiocytic elements in either localized or more widespread form will be elaborated.” Halprin KM, Lorincz AL. Disseminated x…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Metastasizing Dermatofibroma?

“. . . We conclude that dermatofibromas can very rarely metastasize. Risk factors for metastasis may include relatively large size, high cellularity, and local recurrence. It would appear that metastasizing dermatofibromas behave in an indol…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Origin of Adnexal Neoplasms?

“Thus one needs to bear in mind the information required of a pathologist about a particular tumour, which can be summarized as follows: 1. What is the origin of the tumour? 2. What is likely the behavior of the tumour? 3. What is the extent…