Search Results for: histiocytes

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Cytophagic Panniculitis?

…ackwell Scientific Publications, 1992:2146–47. “Panniculitis can be a feature of malignant histiocytosis, but the histiocytes have the cytological features of neoplastic cells, in contrast to cytophagic histiocytic panniculitis where the…

Histologic Diagnosis of Inflammatory Skin Diseases

Rheumatoid nodule

…Differential diagnosis histopathologic Subcutaneous granuloma annulare contains abundant mucin in the center of palisades of histiocytes and scant, if any, fibrin. Necrobiosis lipoidica shows striking degeneration of collagen in the center of…

Histologic Diagnosis of Inflammatory Skin Diseases

Dermatofibroma

…sometimes, in the upper part of the subcutaneous fat Proliferation of small blood vessels in the region of the infiltrate of histiocytes Histiocytes at the periphery of the nodule “splayed” between thickened bundles of collagen…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…neutrophils = Xanthogranuloma, fully developed Early in its course, xanthogranuloma consists of a monomorphous infiltrate of histiocytes that are nearly devoid of foamy cytoplasm. When fully developed, as here, the infiltrate is mixed and composed…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…and necrosis of inflammatory cells in the upper part of the dermis. = Crohn’s disease In addition to the preponderant histiocytes, lymphocytes, plasma cells, and eosinophils are present in the infiltrate. 10.15.3A: Nodular dermatitis,…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…ues which, itself, is one of many expressions morphologic of mycosis fungoides. Error: Ground-glass cytoplasm is specific to histiocytes of reticulohistiocytic granuloma. Reason: Not only does the cytoplasm of those histiocytes bear no resemblance…

Histologic Diagnosis of Inflammatory Skin Diseases

Foreign body reaction

…s fat Rupture of an infundibular cyst is recognized by the presence of individual cornified cells (squames) in multinucleate histiocytes and of hair shafts either in a zone of suppuration or fibrosis, or surrounded by histiocytes. Splinters display…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…brosing inflammation characteristic of that distinctive panniculitis. 10.33.8A: Panniculitis, septal and lobular + 10.33.8B: Histiocytes, some of them multinucleate, in company with lymphocytes in widened fibrous septa and patchy infiltrates of…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

histiocytes usually 7. Neither large nuclei nor large nucleoli in histiocytes 7. Both large nuclei and prominent nucleoli in histiocytes 8. No mitotic figures in histiocytes usually 8. Mitotic figures in scattered histiocytes 9. Few neutrophils at…