Search Results for: hypergranulosis

Keratotic papules of palms and soles

Keratotic papules of palms and soles

…umerous depressed pits of different sizes on the soles. [Copyright: ©2015 Maione et al.] Figure 3. Epidermal depression with hypergranulosis and marked orthokeratotic hyperkeratosis (H & E, magnification 2x). [Copyright: ©2015 Maione et al.]…

Differential Diagnosis in Dermatopathology

Lichen planus vs. Lichenoid discoid lupus erythematosus

Loss of hair attributable either to the effects of inflammatory cells on follicles or to physiological or mechanical factors in which inflammatory cells play no role. Although the scalp is the site most often affected, any region of the skin that…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…aper thin 1. Epidermis sometimes paper-thin 2. Wedge-shaped hypergranulosis in foci in repeatable fashion 2. No wedge-shaped hypergranulosis as a rule; hypergranulosis without a wedge episodic and not in repeatable pattern 3. Cleft between atrophic…

Widespread pruritic papules on the trunk and extremities

Widespread pruritic papules on the trunk and extremities

…anation Generalized lichen amyloidosis. On histopathological examination, epidermal changes including marked hyperkeratosis, hypergranulosis, and irregular acanthosis were observed. An additional finding was the presence of eosinophilic, hyaline,…

Differential Diagnosis in Dermatopathology

Alopecia of discoid lupus erythematosus vs. Alopecia of lichen planus

Loss of hair attributable either to the effects of inflammatory cells on follicles or to physiological or mechanical factors in which inflammatory cells play no role. Although the scalp is the site most often affected, any region of the skin that…

Histologic Diagnosis of Inflammatory Skin Diseases

Persistent light reaction

…are present in the bandlike infiltrate. The findings of lichen simplex chronicus are recognizable as compact orthokeratosis, hypergranulosis, uneven psoriasiform acanthosis, and a papillary dermis thickened by coarse bundles of collagen arranged in…

Differential Diagnosis in Dermatopathology

Lichen sclerosus et atrophicus vs. Superficial morphea

Loss of hair attributable either to the effects of inflammatory cells on follicles or to physiological or mechanical factors in which inflammatory cells play no role. Although the scalp is the site most often affected, any region of the skin that…