Histologic Diagnosis of Inflammatory Skin Diseases

Images

…t is situated at a site where a pustule, housed at first in an infundibulum, had been scratched, a discrete ulcer marking that spot. The perivascular and interstitial infiltrate is secondary to rupture of an infundibulum not seen in this section. The…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Apocrine Miliaria?

…s; spongiosis at the site of entry of an apocrine duct into an infundibulum is a phenomenon secondary, i.e., consequent to an infundibulum blocked by cornified cells. In brief, the essential process pathologic in Fox-Fordyce disease is not seated in…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Inverted Follicular Keratosis, Tricholemmoma, and Desmoplastic Tricholemmoma?

“For about the last 8 years my associates and I have been observing a lesion—a keratosis—which occurs mostly on the face: I should say about 90 percent on the face, the remainder on other parts of the body. These lesions are characterized cli…

Histologic Diagnosis of Inflammatory Skin Diseases

Apocrine Units

…dermis (Fig. 1.54). Figure 1.54 An apocrine duct enters the infundibulum of an epidermis above the entry of a sebaceous duct, which is at the junction of infundibulum and isthmus. The duct then spirals through infundibular epidermis in a fashion s…

Differential Diagnosis in Dermatopathology

Discussions

Perforating folliculitis and elastosis perforans serpiginosa have several findings histopathologic in common: an epithelial channel through surface epidermis; neutrophils in the channel; a collection of neutrophils contiguous with the channel; foci…

Differential Diagnosis in Dermatopathology

Perforating folliculitis vs. Elastosis perforans serpiginosa

An enlargement of normal pre-existing sebaceous lobules on the face, the forehead, cheeks, and nose in particular, that results in lesions seen clinically to consist of a rim of yellow papules around a central dell that represents a dilated ostium o…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

In this section, algorithms used to reach specific diagnosis are predicated on “nonspecific” findings recognized best at higher magnification. Other changes requisite for specific diagnoses, i.e., denominators that are essential, then ar…