Search Results for: itch-scratch sequence

Murphy MJ (ed). Molecular Diagnostics in Dermatology and Dermatopathology. New York: Springer Science + Business Media (Humana Press), 2011

Murphy MJ (ed). Molecular Diagnostics in Dermatology and Dermatopathology. New York: Springer Science + Business Media (Humana Press), 2011

…ollowing binding of the primer to one strand, why not the entire strand? Why is the PCR product restricted to a short target sequence? The authors do not mention the fact that a pair of primers is required, binding to different loci adjacent to the…

Histologic Diagnosis of Inflammatory Skin Diseases

The Algorithmic Method

An algorithm is a method for calculation based on logical thought and orderly sequence, one that can be utilized for diagnosis of diseases of all kinds, including inflammatory ones of the skin. Once a disorder of the skin and/or subcutaneous fat…

Histologic Diagnosis of Inflammatory Skin Diseases

Nail Units

…he isthmus, the outer sheath there cornifies in a distinctive unfettered fashion. When a nail separates from its bed as a consequence of a variety of processes pathologic, the epithelium of the bed proceeds to cornify in an equally unrestrained…

Hypertrophic lichen planus versus prurigo nodularis: a dermoscopic perspective

Hypertrophic lichen planus versus prurigo nodularis: a dermoscopic perspective

…urodermatitis of unclear etiology characterized by excoriated, intensely pruritic nodules, which are secondary to an intense itchscratch cycle (Figure 1b). It was first described by Hardaway in 1880 and named by Hyde and Montgomery in 1909 [2]. It…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Dandruff a Disease?

…filthinesse of the head called in Latin Perrigo, in English the dandruffe of the head, the which is, when at the kembing and scratching of the head, certaine white scales, as it were branne, falleth off from the head, and lyeth very thick among and…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Changing Mole?

…ey cease growing almost entirely. Such change is expected. Miescher’s nevi on the face that enlarge and redden as a consequence of rupture of an infundibular cyst beneath them with subsequent induction of suppuration, granulomatous…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Xerosis, Asteatosis, Asteatotic Eczema, Eczema Craquelé, and Dry Skin?

…ition is called dandruff. It may well be that because of the upright posture of man and changes of inevitable stasis as a consequence, scales of the stratum disjunction on the legs, rather than being invisible as they are normally on all other sites…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen simplex chronicus/Prurigo nodularis/Picker’s nodule/Erosions/Ulcers

…enic. So-called atopic dermatitis is not a disease of the skin sui generis, but rather the result of animated rubbing and of scratching skin that itches by virtue of a combination of influence genetic, i.e., the atopic state (for which reason mucous…