Histologic Diagnosis of Inflammatory Skin Diseases

Acroangiodermatitis of Mali/Stewart-Bluefarb syndrome

An inflammatory process expressed clinically by markedly edematous acuminate papules and edematous plaques situated mostly on the face, upper part of the trunk, and arms, especially the hands, and often accompanied by fever and leukocytosis. It may…

Histologic Diagnosis of Inflammatory Skin Diseases

Sweet’s syndrome

An inflammatory process expressed clinically by markedly edematous acuminate papules and edematous plaques situated mostly on the face, upper part of the trunk, and arms, especially the hands, and often accompanied by fever and leukocytosis. It may…

Histologic Diagnosis of Inflammatory Skin Diseases

Toxic shock syndrome

An inflammatory process expressed clinically by markedly edematous acuminate papules and edematous plaques situated mostly on the face, upper part of the trunk, and arms, especially the hands, and often accompanied by fever and leukocytosis. It may…

Histologic Diagnosis of Inflammatory Skin Diseases

Behçet’s Disease

…ent Panniculitis is one of many expressions of Behçet”s syndrome. The lesions often are described as “erythema nodosum-like,” a term that is valid because panniculitis in Behçet”s syndrome resembles erythema nodosum clinically…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…abnormalities shared by lupus erythematosus, Sjögren’s syndrome, systemic sclerosis, rheumatoid arthritis, and polyarteritis nodosa. Reason: Those five diseases largely are unrelated to one another and, moreover, abnormalities of collagen and…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Churg-Strauss Granuloma and Allergic Granulomatosis?

“The occurrence of a clinical syndrome of severe asthma, fever, and hypereosinophilia, together with symptoms of vascular embarrassment in various organ systems, has been established. . . . The basic anatomical changes . . . consisted of wide…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Sclerotic Fibroma?

…ry or multiple, discrete skin nodules in patients with Cowden syndrome. Oral SF has been reported in patients with Cowden syndrome; however we now report the first documented series of sporadic SF originating within the oral mucosa.” Alawi F, F…

Histologic Diagnosis of Inflammatory Skin Diseases

Impetigo contagiosa

…contagiosa, bullous impetigo, and staphylococcal scalded skin syndrome, all of which are caused by Gram-positive bacteria, but are very different from one another in certain respects. Clinically, lesions of impetigo contagiosa consist of pustules tha…

Histologic Diagnosis of Inflammatory Skin Diseases

Arthropod assaults

…o polymorphous light eruption, dermatophytosis, Sweet’s syndrome, erysipelas, and several other “acute” inflammatory conditions that are either devoid of eosinophils or sport relatively few of them. An infiltrate of inflammatory cel…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Nodular and Diffuse Dermatitis

…dermatitis with predominance of neutrophils is Sweet’s syndrome (Fig. 5.205 A&B), which may be simulated histopathologically by bowel-bypass syndrome and one of the presentations of pyoderma gangrenosum (Fig. 5.206 A&B). Sometimes mono…