Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Keratosis Lichenoides Chronica?

“So we have to start once more [in regard to what is the authentic nature of lichen rubra moniliformia], returning to the old case of Kaposi by which the question began in 1886.” Pinkus H. Lichen ruber moniliformis Kaposi. Arch Dermato…

Differential Diagnosis in Dermatopathology

Granular-cell tumor vs. Xanthoma

An inflammatory process that develops secondary to trauma, usually in the form of a penetrating injury or rupture of a follicle, and that proceeds through stages of granulation tissue with numerous extravasated erythrocytes, granulomatous inflammati…

Histologic Diagnosis of Inflammatory Skin Diseases

Dermatofibroma

Dermatofibroma Synonyms Benign fibrous histiocytoma Fibroma dura Subepidermal nodular sclerosis Histiocytoma Histiocytoma cutis Sclerosing hemangioma Fibroma simplex or fibroma durum Nodulus cutaneus Fibrome en Pastille Dermatofibroma lenticulare De…

Differential Diagnosis in Dermatopathology

Discussions

Erythematous papules of acne vulgaris and of rosacea have in common localization mostly to the face, suppurative infundibulitis, and a mixed infiltrate of inflammatory cells in the dermis, it containing lymphocytes and plasma cells, and sometimes hi…

Differential Diagnosis in Dermatopathology

Discussions

The most important finding that granular-cell tumors and xanthomas have in common is diffuse dermal infiltrates of monomorphous cells that possess abundant pale-staining cytoplasm. The cytoplasm may have either a basophilic or eosinophilic hue in se…

Differential Diagnosis in Dermatopathology

Acne vulgaris, erythematous papule vs. Rosacea, erythematous papule

An inflammatory process that develops secondary to trauma, usually in the form of a penetrating injury or rupture of a follicle, and that proceeds through stages of granulation tissue with numerous extravasated erythrocytes, granulomatous inflammati…