Search Results for: melanocytes

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Persistent Lentiginous Melanocytic Hyperplasia, Atypical Melanocytic Hyperplasia (Melanocytic Nuclear Atypia), Lamellar Fibroplasia, Concentric Fibroplasia, and Lymphocytes as Criteria for Diagnosis Histopathologic of Dysplastic Nevi?

…ouette when formed fully, i.e., compound, symmetrical, well-circumscribed, slightly elevated, and composed of small nests of melanocytes situated at the dermoepidermal junction and in the papillary dermis. It seems simple—and it is! “The…

Melanocytic nevi and melanoma: overlapping criteria—the degree is the key

Melanocytic nevi and melanoma: overlapping criteria—the degree is the key

…igure 2. Melanocytic nevus on the back of a 60 year-old male. (A) (H&E) There are round and elongated confluent nests of melanocytes along with crowded solitary melanocytes with monomorphous small, round-oval nuclei with paltry cytoplasm, at the…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lentigo Maligna?

…rmis are not equidistant from one another, vary considerably in size and shape, and have become confluent in loci. Moreover, melanocytes disposed as solitary units predominate over nests in some high-power fields, and some melanocytes are present…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Halo Phenomenon?

…ry different from those of Clark, to wit, the silhouette of a benign neoplasm, slight elevation, and confinement of nests of melanocytes with small, oval, monomorphous nuclei to the dermoepidermal junction and the papillary dermis. The changes in…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Radial Growth Phase versus Vertical Growth Phase of Melanoma?

…s III (neoplastic melanocytes filling the papillary dermis and causing the reticular dermis to become bowed), IV (neoplastic melanocytes within the reticular dermis), and V (neoplastic melanocytes in the subcutaneous fat). Changing the names to…

Differential Diagnosis in Dermatopathology

Discussions

…identity. In actuality, those cells conventionally termed “nevus cells,” “nevocytes,” and “nevomelanocytes” are abnormal melanocytes. Lentigo maligna (Hutchinson’s freckle, melanosis circumscripta…

Differential Diagnosis in Dermatopathology

Discussions

…bove the dermoepidermal junction and sometimes being present at all levels of the epidermis) and the dermis, some neoplastic melanocytes in mitosis, and an infiltrate of lymphocytes in the dermis. In actuality, nuclear abnormalities of melanocytes

Acral melanoma with hyperkeratosis mimicking a pigmented wart

Acral melanoma with hyperkeratosis mimicking a pigmented wart

…ually made. Figure 3. (A) Hematoxylin and eosin staining revealed remarkable hyperkeratosis and many large nests of atypical melanocytes at the dermoepidermal junction. (B) Nests of atypical melanocytes ascending into the stratum corneum. (C) The…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Dysplasia?

…atypical mole, and atypical mole syndrome. “It has been stated that the peripheral extent of growth of intraepidermal melanocytes defines the lateral margins of the dermal component of nevi and that the nesting of melanocytes within the…