Search Results for: metastatic squamous-cell carcinoma

Therapeutic Strategies in Dermatology

Porokeratosis: Overview

…orokeratosis should be biopsied to exclude the development of squamous cell carcinoma. Pitfalls The diagnosis of porokeratosis should be confirmed by biopsy prior to initiating therapy. Porokeratosis may be premalignant. Any papule, nodule, or ulcer…

Therapeutic Strategies in Dermatology

Lichen Sclerosus et Atrophicus: Overview

…the genitalia is associated with an increased risk of genital squamous cell carcinoma, and patients should be followed for this possibility. Topical tacrolimus may increase the risk for the development of neoplasia. Superpotent topical steroid treatm…

Therapeutic Strategies in Dermatology

Warts: Initial Evaluation

…itial Evaluation Common warts (verruca vulgaris) Plantar wart (verruca plantaris) Flat warts (verruca plana) Genital warts (condyloma acuminata) Bowenoid papulosis Differential diagnosis Actinic keratoses Squamous cell carcinoma Seborrheic keratoses…

Therapeutic Strategies in Dermatology

Granuloma Inguinale: Overview

…ies are required to establish the diagnosis and to rule out a squamous cell carcinoma in some cases. Early discontinuation of treatment leads to more frequent relapse. Although gentamicin is highly effective, restrict its use to patients who fail to…

Therapeutic Strategies in Dermatology

Candidiasis: Treatment

…need a biopsy to rule out extramammary Paget’s disease, squamous cell carcinoma in situ (Bowen’s disease), and metabolic and other inflammatory causes of an intertriginous eruption. Oral ketoconazole, in rare cases, may cause liver functi…

Therapeutic Strategies in Dermatology

Epidermolysis Bullosa: Overview

…ng ulcer should be carefully evaluated for the possibility of squamous cell carcinoma. Repeated surgical procedures may be required to release mitten hands and keep digits functional. Regular endoscopic esophageal dilation may be required. Regular im…

Differential Diagnosis in Dermatopathology

Metastatic carcinoma from a breast vs. Morpheiform basal-cell carcinoma

Extramammary Paget’s disease is an apocrine carcinoma that begins within the epidermis and presents itself clinically as a patch or a subtle plaque that extends centrifugally for many years before becoming a readily discernible thick plaque, a…

Therapeutic Strategies in Dermatology

Dermatomyositis: Overview

…crease in the risk of internal malignancy, especially ovarian carcinoma in women. Appropriate screening is required for all adult DM patients, at the time of diagnosis and at regular intervals, even those patients with amyopathic DM. A myopathy resem…

Therapeutic Strategies in Dermatology

Balanitis: Overview

…onding to conventional therapy should be biopsied to rule out carcinoma in situ (erythroplasia). Since the diagnosis of balanitis is nonspecific, therapeutic strategy differs depending on the suspected or demonstrated clinical diagnosis. Treatment Er…