Search Results for: morphea

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…dated. It seems, however, to be unique, surely different from morphea and scleromyxedema. 10.69.2A: Fibrosing dermatitis, panniculitis, septal, and fasciitis + 10.69.2B: Fibrocytes scattered among wavy bundles of collagen = Nephrogenic fibrosing derm…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Perivascular Dermatitis

…mes in the interstitium of the reticular dermis of lesions of morphea at an early stage of that process (Fig. 5.32 A&B). Figure 5.27 A&B. Diagnosis with near specificity. A perivascular and interstitial infiltrate of lymphocytes especially ar…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Overlap Syndromes?

…s and lichen planus, seborrheic dermatitis and psoriasis, and morphea and lichen sclerosus et atrophicus. On the basis of our study of lesions reputed to be representative of overlap syndromes, we have come to a different conclusion, namely, that the…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Perivasculitis?

…’s disease. Arch Dermatol 1981;117:674–75. “Morphea, or localized scleroderma, of the eyelids is an uncommon disease. . . . In the present report a patient with biopsy-proven morphea of both upper eyelids is described. The salient h…

Histologic Diagnosis of Inflammatory Skin Diseases

Graft-versus-host disease/Eruption of lymphocyte recovery

…graft-versus-host disease are indistinguishable from those of morphea as it is encountered in circumstances as dissimilar as in Shulman’s syndrome and porphyria cutanea tarda. Morphea, like erythema multiforme, erythema nodosum, leukocytoclasti…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…uation in granuloma annulare, may have a cerebriform outline. Morphea differs from interstitial mycosis fungicides by the infiltrate tending to be “bottom heavy” and containing plasma cells and eosinophils, in addition to lymphocytes. Eos…

Histologic Diagnosis of Inflammatory Skin Diseases

Necrobiosis lipoidica

…septa, a finding reminiscent of changes in the panniculus of morphea. In morphea, however, septa are devoid of granulomatous inflammation and they are widened by crowded, thickened bundles of collagen oriented parallel to one another. So-called subc…

Histologic Diagnosis of Inflammatory Skin Diseases

Limitations of the Algorithmic Method

…involved at all. Notable exceptions to that general rule are morphea (see Fig. 5.32), necrobiosis lipoidica, and interstitial granulomatous dermatitis with arthritis, many examples of those three conditions being “bottom heavy,” consisti…