Search Results for: necrobiosis

Differential Diagnosis in Dermatopathology

Discussions

…often are surrounded by numerous foamy histiocytes that enable necrobiotic xanthogranuloma to be differentiated easily from necrobiosis lipoidica, in which there are none. Foam cells and calcification are consequences of necrosis of adipocytes in…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…in quality of staining, i.e., the usual red hue becomes blue. These changes in collagen are seen in conditions as unalike as necrobiosis lipoidica, necrobiotic xanthogranuloma, and severe burns of any cause, and as a consequence of the effects of…

Histologic Diagnosis of Inflammatory Skin Diseases

The Algorithmic Method

…lasm. Figure 6.3 A&B. Identification of plasma cells at scanning and high magnifications. Plasma cells in this lesion of necrobiosis lipoidica are seen, at scanning magnification, to be more pale than lymphocytes but more dark than histiocytes,…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…moreover, abnormalities of collagen and of blood vessels are not unique to them (witness diseases as different from them as necrobiosis lipoidica and necrobiotic xanthogranuloma, both of which affect profoundly collagen and blood vessels). Error:…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…uloma annulare, where deposits of mucin in foci are invariable, no mucin is detectable in association with the granulomas of necrobiosis lipoidica. 10.43.4A: Nodular dermatitis, granulomatous + 10.43.4B: Histiocytes in palisaded array around a focus…

Rongioletti F, Smoller BR (eds). Clinical and Pathological Aspects of Skin Diseases in Endocrine, Metabolic, Nutritional and Deposition Disease. New York: Springer; 2010

Rongioletti F, Smoller BR (eds). Clinical and Pathological Aspects of Skin Diseases in Endocrine, Metabolic, Nutritional and Deposition Disease. New York: Springer; 2010

…diseases summarized in this book. In particular, some of the images not to be missed include beautiful clinical examples of necrobiosis lipoidica (Fig. 2.1), pretibial myxedema (plaque-type) (Fig. 3.2), acromegaly (Fig. 4.1), eruptive xanthoma…