Search Results for: necrobiosis

Study By Disease

Study By Disease

…que (Quiz #558) Mycosis fungoides, plaque and patch stages (Quiz #632) Myiasis (Quiz #604) Necrobiosis lipoidica (Quiz #184) Necrobiosis lipoidica (Quiz #185) Necrobiosis lipoidica (Quiz #262) Necrobiosis lipoidica (Quiz #301) Necrobiosis lipoidica…

Differential Diagnosis in Dermatopathology

Xanthogranuloma vs. Necrobiotic xanthogranuloma

A granulomatous inflammatory process characterized clinically by patches that become yellowish plaques and that in time resolve with atrophy and telangiectases. The condition usually occurs in persons with diabetes.

Histologic Diagnosis of Inflammatory Skin Diseases

Miescher’s granuloma of the face

…embling leprosy. Int J Lepr 1964;32: 368–70. Mehregan AH, Altman J. Miescher’s granuloma of the face. A variant of the necrobiosis lipoidica-granuloma annulare spectrum. Arch Dermatol 1973;107:62–64. O’Brien JP. Actinic granuloma. An…

Differential Diagnosis in Dermatopathology

Discussions

…often are surrounded by numerous foamy histiocytes that enable necrobiotic xanthogranuloma to be differentiated easily from necrobiosis lipoidica, in which there are none. Foam cells and calcification are consequences of necrosis of adipocytes in…

Actinic granuloma

Actinic granuloma

…giant cells, which phagocytize the degenerated elastic fibers, a process known as elastophagocytosis. There is an absence of necrobiosis, such as facial necrobiosis lipoidica, or mucinosis, such as GA or sarcoid-like granuloma in the dermis at the…

Histologic Diagnosis of Inflammatory Skin Diseases

The Algorithmic Method

…lasm. Figure 6.3 A&B. Identification of plasma cells at scanning and high magnifications. Plasma cells in this lesion of necrobiosis lipoidica are seen, at scanning magnification, to be more pale than lymphocytes but more dark than histiocytes,…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…moreover, abnormalities of collagen and of blood vessels are not unique to them (witness diseases as different from them as necrobiosis lipoidica and necrobiotic xanthogranuloma, both of which affect profoundly collagen and blood vessels). Error:…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…in quality of staining, i.e., the usual red hue becomes blue. These changes in collagen are seen in conditions as unalike as necrobiosis lipoidica, necrobiotic xanthogranuloma, and severe burns of any cause, and as a consequence of the effects of…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…uloma annulare, where deposits of mucin in foci are invariable, no mucin is detectable in association with the granulomas of necrobiosis lipoidica. 10.43.4A: Nodular dermatitis, granulomatous + 10.43.4B: Histiocytes in palisaded array around a focus…