Differential Diagnosis in Dermatopathology

Differential Diagnosis

…affect the subcutaneous fat 11. Granular cells in cutaneous nerves 11. No foam cells in cutaneous nerves 12. Little fibrosis 12. Marked fibrosis at times 13. No extracellular lipid 13. Extracellular lipid nearly invariable in “eruptive&#…

Differential Diagnosis in Dermatopathology

Granular-cell tumor vs. Xanthoma

An inflammatory disease caused by Mycobacterium leprae. It can involve internal organs or be localized to the skin, where its clinical presentation is dependent on the immunologic status of the host. Persons who are competent immunologically have pa…

Histologic Diagnosis of Inflammatory Skin Diseases

Suggested Readings

General Balkwill F (ed). Cytokine Cellular Biology: A Practical Approach (Practical Approach Series). Oxford: Oxford University Press, 2000. Darmon M, Blumenberg M (eds). Molecular Biology of the Skin: The Keratinocyte. San Diego: Academic Press, 19…

Dermatology Practical & Conceptual

Spitz and Reed nevi: acquired or congenital?

Objective Although conflicting with the concept of nevi being hamartomas, to date, Spitz and Reed nevi have been regarded as acquired melanocytic nevi, whereas many other types have already been accepted as being congenital. Here, the reader will fi…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Nevus Cells, Nevocytes, and Nevomelanocytes?

“A nevus (mole) is a benign neoplasm of pigment-forming cells, the nevus cell.” Lookingbill DP, Marks JG Jr. Principles of clinical diagnosis. In: Moschella SL, Hurley HJ, eds. Dermatology. 3rd ed. Philadelphia, PA: WB Saunders Co., 19…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Psychocutaneous Disorders?

“The influence of the psyche on the skin is greater than on any other organ. It is apparent in the many cutaneous expressions of the emotions, subjective, as well as objective, both in man and in animals. It is for this reason that the skin i…

Histologic Diagnosis of Inflammatory Skin Diseases

Chondrodermatitis nodularis helicis

Chondrodermatitis nodularis helicis Presentation stereotypical Age and sex White men mostly Distribution of lesions Localized to the helix or anthelix Individual lesions Papule or nodule often crusted or keratotic, but sometimes smooth; an early pap…