Differential Diagnosis in Dermatopathology

Differential Diagnosis

…affect the subcutaneous fat 11. Granular cells in cutaneous nerves 11. No foam cells in cutaneous nerves 12. Little fibrosis 12. Marked fibrosis at times 13. No extracellular lipid 13. Extracellular lipid nearly invariable in “eruptive&#8…

Differential Diagnosis in Dermatopathology

Granular-cell tumor vs. Xanthoma

An inflammatory disease caused by Mycobacterium leprae. It can involve internal organs or be localized to the skin, where its clinical presentation is dependent on the immunologic status of the host. Persons who are competent immunologically have pa…

Histologic Diagnosis of Inflammatory Skin Diseases

Suggested Readings

…of hair erection. Dermatopathol Pract Concept 1995;1:229-233. Nerves Johnson KO. The roles and functions of cutaneous mechanoreceptors. Curr Opin Neurobiol 2001;11:455-461. Johnson KO, Yoshioka T, Vega-Bermudez F. Tactile functions of mechanorecepti…

Dermatology Practical & Conceptual

Spitz and Reed nevi: acquired or congenital?

…subcutis and involvement of cutaneous appendages, vessels or nerves. As a common finding, melanocytes splay between collagen bundles singly or in double rows [4,10,11]. Recently, the presence of largish melanocytic nests has been identified as a fur…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Nevus Cells, Nevocytes, and Nevomelanocytes?

…cytes in the lower dermis being derived from Schwann cells of nerves.” Rhodes AR. Neoplasms: benign neoplasias, hyperplasias, and dysplasias of melanocytes. In: Fitzpatrick TB, Eisen AZ, Wolff K, et al., eds. Dermatology in General Medicine. 4…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Psychocutaneous Disorders?

…air follicles in response to powerful emotions? Skin contains nerves that are integral to the peripheral nervous system. As long as mortals think and feel, the effects of those thoughts and feelings will be communicated to the skin. It is not surpris…

Histologic Diagnosis of Inflammatory Skin Diseases

Chondrodermatitis nodularis helicis

…ons of p75 nerve growth factor receptor-immunoreactive dermal nerves in prurigo nodularis. Arch Dermatol Res 1999;291(1):14-21. Mattila JO, Vornanen M, Katila ML. Histopathological and bacteriological findings in prurigo nodularis. Acta Derm Venereol…