Therapeutic Strategies in Dermatology

Palmar and Plantar Keratoderma: Overview

Overview Palmoplantar keratodermas (PPK) can occur as a primary, inherited disorder of the volar surfaces, or as part of a generalized disorder, such as psoriasis, cutaneous T-cell lymphoma, or ichthyosis. Discussion of treatment here is limited to…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Precursor Lesions of Melanoma?

…;51(5):830-5. What do lentigo maligna, congenital melanocytic nevi, nevi with architectural and cytologic atypia (dysplastic nevi), and acral and mucosal lentiginous melanocytic proliferations have in common? Apart from the fact that all of them are…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Blue Nevus?

…ns, 1992:1538. “On the skin, three types of benign blue nevi are recognized: the common blue nevus, the cellular blue nevus, and the combined nevus. In addition, there are malignant blue nevi. … Histologically, the common feature of blue nevi

Dermatology Practical & Conceptual

Strategies for early recognition of cutaneous melanoma-present and future

…and family history of melanoma, number of common and atypical nevi, skin type, presence of freckles, eye color, hair color, and the presence of non-melanoma skin cancer lesions should be considered [2]. The overall number of nevi induced by ultravio…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Normal, Typical, Ordinary, Banal, and Common Nevus?

…nevus is to designate it normal. In actuality, all melanocytic nevi are abnormal, just as are all seborrheic keratoses and cherry hemangiomas. Because a lesion is common does not make it normal. Were melanocytic nevi normal, students would read about…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Dysplasia?

…#8220;familial melanomas” also bore acquired melanocytic nevi of two types: (1) small “banal” or “ordinary” nevi and (2) large “funny looking moles.” Sections taken from biopsy specimens of funny looking mole…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Junctional Activity and Active Junctional Nevus?

…nevus cells (intradermal nevus).” Weedon D. Lentigines, nevi, and melanomas. In: Skin Pathology. 2nd ed. New York, NY: Churchill-Livingstone, 2002:806. “Intradermal nevi show essentially no junctional activity.” Elder DE, Elenits…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Malignant Spitz Nevus?

…s. Benign proliferations of melanocytes are termed melanocytic nevi (congenital melanocytic nevi are hamartomas, whereas acquired melanocytic nevi, such as those of Clark, Spitz, and Reed, are benign neoplasms), and they, of course, do not metastasiz…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Nevus?

…omposed mostly of melanocytes (e.g., in congenital melanocytic nevi), of keratocytes (e.g., in epidermal nevi), of elements of connective tissue mostly, (e.g., in collagenous nevi, nevus flammeus, and nevus lipomatosus), and of a mixture of elements…