Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Inverted Follicular Keratosis, Tricholemmoma, and Desmoplastic Tricholemmoma?

…say about 90 percent on the face, the remainder on other parts of the body. These lesions are characterized clinically by a papule or nodule, practically always single and usually projecting from the surface. The character of the cells comprising the…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Nevus verrucosus Acanthosis nigricans 1. Orthokeratosis compact 1. Orthokeratosis in basket-woven and lamellate patterns 2. Thick epidermis, either papillated or digitated 2. Thin epidermis 3. Hypergranulosis usually 3. Granular zone normal…

Histologic Diagnosis of Inflammatory Skin Diseases

Advantages of the Algorithmic Method

…rpuric dermatitis Schamberg’s disease Lichenoid purpura of Gougerot and Blum Eczematid-like dermatitis of Doucas and Kapetanakis Diseases secondary to rubbing Lichen simplex chronicus Prurigo nodularis and its analogues (acanthoma fissuratu…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…nes. Only those attributes absolutely necessary for completion of an algorithm successfuly are recorded. Abnormal Lymphocytes in a Mixed-Cell Infiltrate of Inflammatory Cells Lymphocytes with large pleomorphic nuclei in the epidermis, dermis,…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Palpable Purpura?

…ses and along the dermoepidermal junction. The purpuric nature of the papules results from extravasation of erythrocytes in the papillary dermis and often in the epidermis itself. The lichenoid purpura of Gougerot and Blum (lichen aureus), at an earl…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Fibrosing Dermatitis

…ctive bundles of collagen are a clue to a lichenoid infiltrate of lymphocytes having been present for years in the upper part of the dermis. Similar changes may be observed in some examples of long-sustained lesions of the lichenoid purpura of Gouger…

Histologic Diagnosis of Inflammatory Skin Diseases

Acroangiodermatitis of Mali/Stewart-Bluefarb syndrome

…rple patches, plaques, and nodules that simulate closely those of acroangiodermatitis of Mali. Pyogenic granuloma is a solitary friable papule or nodule that early in its course is ulcerated. Lichenoid purpura of Gougerot and Blum, when developed ful…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Necrotizing Vasculitis?

…synonym for leukocytoclastic (allergic) vasculitis (and scors of equivalents for that particular type f vasculitis, among those being Henoch-Sch?nlein and Gougerot-Ruiter types, small-vessel expression of periarteritis nodosa, anaphylactoid purpura,…

Histologic Diagnosis of Inflammatory Skin Diseases

Collagen

…sum; and those typified by long-standing lichenoid infiltrates of lymphocytes, such as lichen planus, disseminated superficial actinic porokeratosis, and some examples of the lichenoid purpura of Gougerot and Blum (and the neoplastic process, mycosis…