Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.39.1A: Infundibulitis, spongiotic, and peri-infundibulitis + 10.39.1B: Predominance of lymphocytes in and around infundibula dilated by corneocytes = Fox-Fordyce disease Spongiosis in the wall of an infundibulum near the site wh…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

….1B: A comedo in association with granulomatous and fibrosing peri-infundibulitis = Acne vulgaris Many of the findings pictured here may be seen in other types of suppurative infundibulitis, but the presence of a comedo in the context of the supp…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…is to be made accurately and with confidence. 10.47.9A: Peri-infundibulitis, mixed-cell + 10.47.9B: Infundibula with ballooned keratocytes, many multinucleate necrotic cells with pyknotic nuclei and some cells with “margination”…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…s pilaris and is noted palpably on palpation. 11.10.2A: Perivascular dermatitis and peri-infundibulitis + 11.10.2B: A plug of cornified cells in a thinned infundibulum that in loci no longer in contiguity with adjacent dermis = Keratosis pi…

Histologic Diagnosis of Inflammatory Skin Diseases

Hair Follicles

…ort distance into the isthmus. What usually is referred to as perifolliculitis really is peri-infundibulitis, affecting as it does the infundibulum mostly. At times, however, infiltrates of inflammatory cells not only surround the infundibulum, but e…

Histologic Diagnosis of Inflammatory Skin Diseases

Majocchi’s granuloma

…only at the apogee of it; the condition begins as suppurative infundibulitis that, in time, becomes suppurative peri-infundibulitis and, not uncommonly, suppurative folliculitis and perifolliculitis, eventually being associated with granulomatous inf…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 11.14.1A: Perivascular dermatosis, psoriasiform lichenoid + 11.14.1B: Lymphocytes, sparse in both the dermis and epidermis, larger in the epidermis than in dermis, solitary in the basal layer in foci, and in association with scant…

Histologic Diagnosis of Inflammatory Skin Diseases

Rosacea

…idiopathic rosacea. Gram-negative “folliculitis” (infundibulitis) presents itself as pustules that develop in patients with acne vulgaris who have received systemic antibiotics for that condition over a long period of time. Discoid lupus…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Fibrosing Dermatitis

…Late (sclerosis). Fibrosing dermatitis (as well as fibrosing peri-infundibulitis/perifolliculitis and fibrosing panniculitis) results, in every instance, from injury to nonepithelial tissue, usually connective tissue, the assault coming either from…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…r folliculitis.” It seems, however, to be a suppurative infundibulitis fundamentally to which has been attracted large numbers of eosinophils. 10.27.2A: Perivascular and interstitial dermatitis + 10.27.2B: Lymphocytes and eosinophils…