Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 11.10.1A: Infundibular plug of corneocytes in a widened infundibulum + 11.10.1B: A cast of parakeratotic cells in the dilated infundibulum = Keratosis pilaris ┬áChanges identical to these are seen in lichen spinulosus, a variant cli…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…pongiosis in infundibula often 16. No peri-infundibulitis or perifolliculitis 16. Peri-infundibulitis and perifolliculitis common 17. No eccrine adenitis 17. Eccrine adenitis sometimes 18. Infiltrate of inflammatory cells not aligned along epit…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Pseudopelade?

“In October, 1888, we presented a review of folliculitis and perifolliculitis decalvans at the Soci?t? m?dicale des h?pitaux, and, at this moment, we have nothing to add; there are three principal clinical types related in some way to one ano…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

In this section, algorithms used to reach specific diagnosis are predicated on “nonspecific” findings recognized best at higher magnification. Other changes requisite for specific diagnoses, i.e., denominators that are essential, then ar…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.108.1A: Section of a biopsy specimen from a scalp + 10.108.1B: Fibrous track widened by thickened collagen bundles and situated in the dermis = Traction alopecia ┬áThese changes are specific for effects of traction on hairs, in c…

Histologic Diagnosis of Inflammatory Skin Diseases

Acne vulgaris

Synonyms Acne simplex Presentation stereotypical Age and sex Adolescents of both sexes; usually more severe in males. May affect neonates. Distribution of lesions Regions in which large sebaceous units are joined to vellus follicles, i.e., the face,…

Differential Diagnosis in Dermatopathology

Discussions

Lichen nitidus and lichen striatus are inflammatory diseases that mostly involve the upper part of the dermis and the epidermis. Both are characterized by a perivascular infiltrate of lymphocytes and histiocytes, lymphocytes and vacuolar alteration…

Differential Diagnosis in Dermatopathology

Discussions

Few subjects are as baffling and frustrating to dermatopathologists than the alopecias. Those aberrations are rivaled in difficulty only by diseases of nail units. Why do those subjects prove to be so recondite? Because biopsies of alopecias and dis…