Differential Diagnosis in Dermatopathology

Discussions

…reaction replete with lymphoid follicles. Nodular lesions of scabies have denser and deeper infiltrates than conventional papules of scabies in which mites and their products, such as fecal nuggets, are housed in burrows in the cornified layer. Othe…

Differential Diagnosis in Dermatopathology

Urticarial reaction to an arthropod assault vs. Urtica

Papules, nodules, vesicles, and sometimes bullae that develop in response to “bites” of arthropods, among the most common offenders being mosquitoes, bedbugs, and mites of scabies….

Histologic Diagnosis of Inflammatory Skin Diseases

Nerves

…ese are dermatitis herpetiformis, Grover’s disease, and scabies. Scratching is thought to relieve itching by disturbing the rhythm of afferent impulses that travel toward the central nervous system. The frequency of nerve impulses associated wi…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…, inflammatory conditions such as insect “bites,” scabies, and Mucha-Habermann disease will be overdiagnosed as lymphoma. The small-vessel vasculitis shown is an epiphenomenon.About 10% of specimens of lymphomatoid papulosis show signs of…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…f it, namely, larvae and nymphs, conducted within a burrow of scabies, namely, ingestion and defecation, gives rise to intense pruritus. The larva or “creeper” of Ancylostoma braziliense, the cause of cutaneous larva migrans, lives in a t…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen simplex chronicus/Prurigo nodularis/Picker’s nodule/Erosions/Ulcers

…s, e.g., dermatitis herpetiformis, Grover’s disease, or scabies. In still other patients, however, no underlying disease, systemic or cutaneous, can be found to explain pruritus, the basis of it in many instances being psychogenic. So-called at…

Histologic Diagnosis of Inflammatory Skin Diseases

Atopic dermatitis

…that may become confluent to form slightly elevated plaques. Scabies favors interdigital webs and other intertriginous zones, and often is typified by the presence of burrows. Acrodermatitis enteropathica is marked by erosions around body orifices a…

Histologic Diagnosis of Inflammatory Skin Diseases

Dermatitis herpetiformis

…actually are grouped, they are not distributed symmetrically; scabies tends to be associated with burrows. Findings histopathologic Early Superficial and, sometimes, deep perivascular infiltrate of lymphocytes mostly and interstitial infiltrate of…