Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Reticular Erythematous Mucinosis?

…ticular erythematous mucinosis Synonyms. REM syndrome, plaque-like cutaneous mucinosis This syndrome comprises areas of reticular erythema on the trunk with a mucinous and round cell infiltrate in the dermis, and is frequently called the REM syndrome…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…to display wrinkling of the surface in a manner that has been likened to that of cigarette paper; in some patients, nodules and tumors come into being, those lesions at times becoming ulcerated. Course Lesions tend to persist, increasing, often slowl…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Perivascular Dermatitis

…of lymphocytes is decidedly “bottom heavy,” it is likely to be a manifestation of a lymphoma, rather than of a dermatitis. Figure 5.23 A. Perivascular dermatitis, superficial. B&C. Lupus tumidus. As a rule, the infiltrate of lympho…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…thematosus, discoid  A thickened epidermal basement membrane, like the one illustrated here, is seen only in classic discoid lupus erythematosus and in dermatomyositis. 10.63.7A: Perivascular dermatitis, interface, vacuolar and peri-infundibuli…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Subcutaneous Fat: Panniculitis

…ration of some lobules and constriction markedly of others. Unlike the situation in erythema nodosum, changes granulomatous similar to those in the subcutaneous fat also are present throughout the reticular dermis of necrobiosis lipoidica. Adipocytes…

Dermatology Practical & Conceptual

The dermatoscopic universe of basal cell carcinoma

…le blue-gray dots/globules, (c) in-focus dots, (d) maple leaf-like areas, (e) spoke wheel areas (arrow) and (f) concentric structures (arrows). [Copyright: ©2014 Lallas et al.] Figure 3. (a) Large dilated vessels in the dermis, corresponding to th…

Differential Diagnosis in Dermatopathology

Discussions

…on neoplastic cells, keratocytes in the case of lichen planus-like keratosis and melanocytes in that of melanoma. A melanoma on sun-damaged skin of a face rarely undergoes regression, whereas a melanoma on a trunk or other covered part not uncommonly…

Histologic Diagnosis of Inflammatory Skin Diseases

Melanocytes

…they possess abundant translucent cytoplasm. The nucleus of a melanocyte is smaller and more deeply basophilic than that of a basal keratocyte, and the cytoplasm of it is dendritic, unlike that of a keratocyte (Fig. 1.63). Dendrites of melanocytes ar…