Histologic Diagnosis of Inflammatory Skin Diseases

Miliaria rubra

…r spongiotic dermatitides differ from miliaria rubra by having spongiosis at sites in the epidermis other than acrosyringia and by spongiosis being more prominent, sometimes eventuating in vesiculation. Clue to specific diagnosis histopathologic Spon…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…rivascular dermatitis, neutrophils predominant + 10.88.4B: Spongiosis mediated by neutrophils and edema of the papillary dermis = Prurigo pigmentosa ¬†Spongiosis is mediated commonly by lymphocytes or eosinophils. In prurigo pigmentosa, spongiosis

Histologic Diagnosis of Inflammatory Skin Diseases

Pemphigus vulgaris

…7;s disease. Last, it should be remembered that an analogue of spongiosis with eosinophils (badly termed “eosinophilic spongiosis”) that occurs in urticarial lesions of pemphigus vulgaris may be found, too, albeit uncommonly, in pemphigus…

Histologic Diagnosis of Inflammatory Skin Diseases

Toxic shock syndrome

Toxic shock syndrome Synonyms TSS Presentation stereotypical Age and sex Women using super-absorbent vaginal tampons especially, but possible in both sexes consequent to any infection by pathogenic bacteria, particularly Staphylococcus aureus, inclu…

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

…r papulovesicular disease characterized histopathologically by spongiosis. That definition, however, excludes a paragon of eczema in most classifications of it, i.e., lichen simplex chronicus (because that condition is devoid of spongiosis) and atopi…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.98.1A: Perivascular dermatitis, and infundibulitis, spongiotic + 10.98.1B: Predominance of lymphocytes and scale-crusts at lips of infundibular ostia = Seborrheic dermatitis ¬†Mounds of scale-crust at lips of infundibular ostia a…

Histologic Diagnosis of Inflammatory Skin Diseases

Fixed drug eruption

Fixed drug eruption Synonyms Fixed toxic exanthem Presentation stereotypical Age and sex Adults of both sexes Distribution of lesions Lips, genital region, and limbs especially Configuration of lesions Round Arrangement of lesions Solitary or few, d…

Histologic Diagnosis of Inflammatory Skin Diseases

Pruritic urticarial papules and plaques of pregnancy

Pruritic urticarial papules and plaques of pregnancy Synonyms Polymorphic eruption of pregnancy Bourne’s toxemic rash of pregnancy Toxemic rash of pregnancy Toxic erythema of pregnancy Nurse’s late onset prurigo of pregnancy Presentati…

Histologic Diagnosis of Inflammatory Skin Diseases

Fox-Fordyce disease

Fox-Fordyce disease Synonyms Apocrine miliaria Presentation stereotypical Age and sex Postpubertal women mostly Distribution of lesions Sites where apocrine glands are numerous, i.e., axillae, periumbilical, pubic, and areolae Arrangement of lesions…