Therapeutic Strategies in Dermatology

Epidermolysis Bullosa: Overview

…ng ulcer should be carefully evaluated for the possibility of squamous cell carcinoma. Repeated surgical procedures may be required to release mitten hands and keep digits functional. Regular endoscopic esophageal dilation may be required. Regular im…

Therapeutic Strategies in Dermatology

Lichen Sclerosus et Atrophicus: Overview

…the genitalia is associated with an increased risk of genital squamous cell carcinoma, and patients should be followed for this possibility. Topical tacrolimus may increase the risk for the development of neoplasia. Superpotent topical steroid treatm…

Therapeutic Strategies in Dermatology

Lichen Planus: Treatment

…sease must be followed for the development of oral or genital squamous cell carcinoma. Optimal oral hygiene is an important adjunctive intervention in the management of oral lichen planus. Furthermore, eliminate potential sources of trauma to the mou…

Therapeutic Strategies in Dermatology

Warts: Initial Evaluation

…taris) Flat warts (verruca plana) Genital warts (condyloma acuminata) Bowenoid papulosis Differential diagnosis Actinic keratoses Squamous cell carcinoma Seborrheic keratoses…

Therapeutic Strategies in Dermatology

Granuloma Inguinale: Overview

…ies are required to establish the diagnosis and to rule out a squamous cell carcinoma in some cases. Early discontinuation of treatment leads to more frequent relapse. Although gentamicin is highly effective, restrict its use to patients who fail to…

Therapeutic Strategies in Dermatology

Actinic Keratosis (a.k.a. Solar Keratosis): References

…Miller DD, et al (2010) Chronic phototoxicity and aggressive squamous cell carcinoma of the skin in children and adults during treatment with voriconazole, JAAD, 62(1):31-37. Criscione VD, Weinstock MA, Naylor MF, et al (2009) Natural history and ri…

Therapeutic Strategies in Dermatology

Candidiasis: Treatment

…need a biopsy to rule out extramammary Paget’s disease, squamous cell carcinoma in situ (Bowen’s disease), and metabolic and other inflammatory causes of an intertriginous eruption. Oral ketoconazole, in rare cases, may cause liver functi…

Therapeutic Strategies in Dermatology

Dermatomyositis: Overview

…crease in the risk of internal malignancy, especially ovarian carcinoma in women. Appropriate screening is required for all adult DM patients, at the time of diagnosis and at regular intervals, even those patients with amyopathic DM. A myopathy resem…

Therapeutic Strategies in Dermatology

Balanitis: Overview

…onding to conventional therapy should be biopsied to rule out carcinoma in situ (erythroplasia). Since the diagnosis of balanitis is nonspecific, therapeutic strategy differs depending on the suspected or demonstrated clinical diagnosis. Treatment Er…