Differential Diagnosis in Dermatopathology

Metastatic carcinoma from a breast vs. Morpheiform basal-cell carcinoma

Papules on skin and mucous membranes that result from infection of keratinocytes by different types of papillomavirus and classified according to their silhouettes, to wit, papillated (verrucae vulgares on different sites such as volar skin, i.e., v…

A Clinical Atlas of 101 Common Skin Diseases

Extramammary Paget’s Disease and Mammary Paget’s Disease

Extramammary Paget’s disease is an apocrine carcinoma that begins within the epidermis and presents itself clinically as a patch or a subtle plaque that extends centrifugally for many years before becoming a readily discernible thick plaque, a…

A Clinical Atlas of 101 Common Skin Diseases

Mammary Paget’s

Mammary Paget’s disease is an apocrine carcinoma that begins in mammary glands and extends along lactiferous ducts to the epidermis where it is seen clinically as a scaly, crusted, or eroded plaque on the nipple or areola of women mostly, and…

Therapeutic Strategies in Dermatology

Candidiasis: Treatment

…need a biopsy to rule out extramammary Paget’s disease, squamous cell carcinoma in situ (Bowen’s disease), and metabolic and other inflammatory causes of an intertriginous eruption. Oral ketoconazole, in rare cases, may cause liver funct…

Therapeutic Strategies in Dermatology

Porokeratosis: Overview

…porokeratosis should be biopsied to exclude the development of squamous cell carcinoma. Pitfalls The diagnosis of porokeratosis should be confirmed by biopsy prior to initiating therapy. Porokeratosis may be premalignant. Any papule, nodule, or ulc…

Therapeutic Strategies in Dermatology

Lichen Planus: Treatment

…isease must be followed for the development of oral or genital squamous cell carcinoma. Optimal oral hygiene is an important adjunctive intervention in the management of oral lichen planus. Furthermore, eliminate potential sources of trauma to the mo…